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成人饮食模式与高血压的纵向研究:中国健康与营养调查 1991-2018。

Longitudinal study of dietary patterns and hypertension in adults: China Health and Nutrition Survey 1991-2018.

机构信息

Key Laboratory of Trace Element Nutrition of National Health Commission, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, No. 29, Nanwei Road, Xicheng District, Beijing, 100050, China.

出版信息

Hypertens Res. 2023 Oct;46(10):2264-2271. doi: 10.1038/s41440-023-01322-x. Epub 2023 Jun 19.

Abstract

China is undergoing the nutrition transition that may explain partly the high prevalence of hypertension. We aimed to investigate the longitudinal association between dietary patterns and hypertension in Chinese adults over 28 years of follow-up. We used data collected in the China Health and Nutrition Survey from 1991 to 2018. Adults aged 18 years and above (n = 15,929) were included in the analysis, for whom questionnaires and anthropometric data were collected during at least two waves. Factor analysis was conducted to derive food patterns based on 18 foods or food groups. We constructed three-level mixed-effect linear regression models to estimate systolic blood pressure (SBP) and diastolic blood pressure (DBP) in relation to quartiles of dietary pattern score and performed three-level mixed-effect logistic regression models to assess the risk of hypertension. Participants in the top quartile of the modern pattern had a decrease in SBP (β = - 0.51; 95% CI -0.86, -0.16; P < 0.01) when adjusted for all potential confounders, whereas participants in the top quartile of the meat pattern had an increase in DBP (β = 0.31; 95% CI 0.08, 0.53; P < 0.01). Participants in the highest quartile of the meat pattern were more likely to have hypertension (OR = 1.14; 95% CI 1.03, 1.24; P < 0.01). Adherence to the modern pattern characterized by high intake of fruits and dairy products was inversely associated with SBP, whereas the meat pattern was positively associated with DBP and the risk of hypertension. These findings may well have important public health implications.

摘要

中国正在经历营养转型,这可能部分解释了高血压的高患病率。我们旨在研究中国成年人在超过 28 年的随访中饮食模式与高血压之间的纵向关联。我们使用了 1991 年至 2018 年期间中国健康与营养调查的数据。分析纳入了年龄在 18 岁及以上的成年人(n=15929),这些人在至少两个时间点接受了问卷调查和人体测量数据采集。基于 18 种食物或食物组,我们采用因子分析得出饮食模式。我们构建了三级混合效应线性回归模型,以评估饮食模式评分四分位数与收缩压(SBP)和舒张压(DBP)之间的关系,并进行了三级混合效应逻辑回归模型,以评估高血压的风险。在调整所有潜在混杂因素后,现代模式评分最高四分位数组的 SBP 下降(β=-0.51;95%CI:-0.86,-0.16;P<0.01),而肉类模式评分最高四分位数组的 DBP 升高(β=0.31;95%CI:0.08,0.53;P<0.01)。肉类模式评分最高四分位数组的参与者更有可能患有高血压(OR=1.14;95%CI:1.03,1.24;P<0.01)。以高水果和乳制品摄入为特征的现代模式与 SBP 呈负相关,而肉类模式与 DBP 和高血压风险呈正相关。这些发现可能具有重要的公共卫生意义。

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