Division of Biological Sciences, University of Missouri, Columbia, MO 65211, USA.
Neuron. 2010 Feb 25;65(4):442-4. doi: 10.1016/j.neuron.2010.02.009.
Gervasi et al. report in this issue of Neuron that the mushroom bodies in Drosophila, a critical center for olfactory memory formation, have spatially restricted PKA activity in response to specific neuromodulators. The dunce cAMP-phosphodiesterase and rutabaga adenylyl cyclase genes are necessary for two key properties of PKA dynamics in these neurons.
格尔瓦西等人在本期《神经元》杂志上报告称，果蝇的蘑菇体（嗅觉记忆形成的关键中心）对特定神经调质的反应具有空间限制的 PKA 活性。傻瓜 cAMP 磷酸二酯酶和 Rutabaga 腺苷酸环化酶基因对于这些神经元中 PKA 动力学的两个关键特性是必需的。
