Services de rhumatologie A, hôpital Cochin, AP-HP, université Paris-Descartes, 27, rue du faubourg 75679 Paris cedex 14, France.
Joint Bone Spine. 2010 Mar;77(2):146-50. doi: 10.1016/j.jbspin.2010.01.001. Epub 2010 Feb 26.
To assess the usefulness of routine electrocardiography for heart disease screening in patients with spondyloarthropathy (SpA) or rheumatoid arthritis (RA).
We included consecutive patients with SpA or RA or with degenerative joint disease (control group) admitted over a 6-month period and free of cardiovascular events. A 12-lead electrocardiogram (ECG) was obtained and was interpreted by a cardiologist who was unaware of the diagnosis.
We included 108 patients with SpA (mean duration, 11+/-10 years), 106 with RA (mean duration, 12+/-9 years), and 74 with degenerative joint disease (controls). No patient had cardiovascular symptoms or a prior history of cardiovascular disease. The only difference in cardiovascular risk factors across the three populations was a higher prevalence of diabetes in the RA and control groups. We found no differences between the SpA or RA groups and the control group regarding the rates of the following ECG findings: premature beats, atrioventricular block (2.8% in the SpA group, 1.9% in the RA group, and 2.7% in the control group), complete or incomplete left bundle branch block (0.9%, 0.9%, and 2.7%, respectively), complete right bundle branch bloc or left bundle branch block (0.9%, 4.7%, and 4.1%, respectively); and abnormalities suggesting myocardial ischemia (10.2%, 19.8%, and 17.6%, respectively).
In patients with SpA or RA who have no cardiovascular symptoms or history of cardiovascular disease, a routine ECG shows no increase in the cardiac abnormalities specifically associated with these joint diseases, compared to controls with degenerative joint disease.
评估常规心电图在脊柱关节炎(SpA)或类风湿关节炎(RA)患者心脏病筛查中的作用。
我们纳入了在 6 个月期间因 SpA 或 RA 或退行性关节病(对照组)住院且无心血管事件的连续患者。获取 12 导联心电图(ECG),并由一位不知道诊断的心脏病专家进行解释。
我们纳入了 108 例 SpA(平均病程 11±10 年)、106 例 RA(平均病程 12±9 年)和 74 例退行性关节病患者(对照组)。没有患者有心血管症状或既往有心血管疾病史。在这三个人群中,心血管危险因素的唯一差异是 RA 和对照组的糖尿病患病率较高。我们发现 SpA 或 RA 组与对照组在以下心电图发现的发生率方面没有差异:早搏、房室传导阻滞(SpA 组 2.8%、RA 组 1.9%、对照组 2.7%)、完全或不完全左束支传导阻滞(0.9%、0.9%、2.7%)、完全右束支阻滞或左束支阻滞(0.9%、4.7%、4.1%);以及提示心肌缺血的异常(10.2%、19.8%、17.6%)。
在无心血管症状或心血管疾病史的 SpA 或 RA 患者中,与退行性关节病对照组相比,常规心电图未显示与这些关节疾病相关的心脏异常增加。