Centre for Human Bioethics, Faculty of Arts, Monash University, Vic 3800, Australia.
Reprod Biomed Online. 2010 May;20(5):667-74. doi: 10.1016/j.rbmo.2009.12.015. Epub 2009 Dec 16.
The creation of 'saviour siblings' is one of the most controversial uses of preimplantation genetic diagnosis (PGD). This paper outlines and invites ethical discussion of an extension of this technology, namely, the creation of 'saviour embryos' to serve as a source of stem cells to be used in potentially life-saving therapy for an existing child. A number of analogies between this hypothetical use of PGD and existing uses of IVF are offered and, in addition, between saviour embryos and proposed therapeutic applications of stem cell technology. The ethical significance of a number of disanalogies between these cases are explored and investigated. While the creation of saviour embryos would involve a significant shift in the rationale for IVF and PGD, it is suggested here that the urgent need of an existing individual should be prioritised over any obligations that might exist in relation to the creation or destruction of human embryos.
“拯救者兄弟姐妹”的创造是胚胎植入前遗传学诊断（PGD）最具争议的用途之一。本文概述并邀请对该技术的扩展进行伦理讨论，即创造“拯救者胚胎”，作为用于现有儿童潜在救生治疗的干细胞来源。提供了这种假设的 PGD 使用与现有 IVF 使用之间的许多相似之处，并且在拯救者胚胎和拟议的干细胞技术治疗应用之间也提供了相似之处。探讨并研究了这些情况下许多不相似之处的伦理意义。虽然拯救者胚胎的创造将涉及对 IVF 和 PGD 基本原理的重大转变，但这里建议，应该优先考虑现有个人的迫切需求，而不是与创造或破坏人类胚胎相关的任何义务。
