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老年患者双气囊小肠镜检查:安全性、检查结果以及诊断和治疗成功率。

Double-balloon enteroscopy in the elderly: safety, findings, and diagnostic and therapeutic success.

机构信息

Division of Gastroenterology and Hepatology, University of Maryland Medical Center, Baltimore, Maryland, USA.

出版信息

Gastrointest Endosc. 2010 May;71(6):983-9. doi: 10.1016/j.gie.2009.10.054. Epub 2010 Mar 1.

Abstract

BACKGROUND

Double-balloon enteroscopy (DBE) is an important tool in the evaluation and management of small-bowel disease. Limited data are available on the safety, findings, and outcomes of DBE in elderly patients.

OBJECTIVE

To determine the safety and efficacy of DBE in elderly patients.

DESIGN

Single-center, retrospective analysis of prospectively collected database.

SETTING

Open-access, tertiary care referral center.

PATIENTS

A total of 176 patients undergoing DBE (216 procedures) for evaluation of small-bowel disease between August 2007 and August 2008.

INTERVENTIONS

Argon plasma coagulation of bleeding small-bowel lesions.

MAIN OUTCOME MEASUREMENTS

DBE complication rate, diagnostic/therapeutic success of DBE.

METHODS

An age cutoff of 75 years and older was used to designate patients as elderly. Data on complications, indications, findings, and diagnostic and therapeutic success of DBE were compared between age groups.

RESULTS

The mean age of patients was 66 +/- 16.4 years (range 20-95 years). DBE was performed in 185 patients, including 60 patients age 75 years and older and 110 patients younger than age 75. An overall complication rate of 0.9% was seen for DBE in this study, with no significant difference between age groups. No major complications were observed in elderly patients. Elderly patients were more likely to have angioectasias (39% vs 23%; P = .01) and were more likely to require endoscopic therapy during DBE (46.8% vs 29.2%; P = .01).

LIMITATIONS

Single-center, retrospective study.

CONCLUSIONS

DBE is safe in elderly patients. Elderly patients are more likely to have angioectasias and to require endoscopic therapy during DBE.

摘要

背景

双气囊小肠镜(DBE)是评估和治疗小肠疾病的重要工具。关于老年患者 DBE 的安全性、检查结果和结局的数据有限。

目的

确定 DBE 在老年患者中的安全性和有效性。

设计

前瞻性收集数据库的单中心回顾性分析。

设置

开放接入的三级保健转诊中心。

患者

2007 年 8 月至 2008 年 8 月期间,共有 176 例接受 DBE(216 例)检查小肠疾病的患者。

干预措施

氩等离子凝固治疗出血性小肠病变。

主要观察指标

DBE 并发症发生率、DBE 的诊断/治疗成功率。

方法

将年龄大于或等于 75 岁的患者定义为老年患者。比较两组患者的并发症、适应证、检查结果以及 DBE 的诊断和治疗成功率。

结果

患者的平均年龄为 66 +/- 16.4 岁(范围 20-95 岁)。本研究中 DBE 在 185 例患者中进行,包括 60 例年龄大于或等于 75 岁的患者和 110 例年龄小于 75 岁的患者。DBE 的总体并发症发生率为 0.9%,两组之间无显著差异。老年患者未发生严重并发症。老年患者更易出现血管扩张(39%比 23%;P =.01),更有可能在 DBE 期间需要内镜治疗(46.8%比 29.2%;P =.01)。

局限性

单中心、回顾性研究。

结论

DBE 在老年患者中是安全的。老年患者更易出现血管扩张和需要 DBE 期间的内镜治疗。

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