Division of Dermatology, Department of Medicine, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, California, USA.
J Am Acad Dermatol. 2010 Sep;63(3):507-25. doi: 10.1016/j.jaad.2009.07.037. Epub 2010 Mar 1.
With the rise of the cosmeceutical industry, numerous formulations have surfaced with claims of reducing the clinical manifestations of photoaging. Many of these products capitalize on the positive connection the public makes with vitamins, especially with respect to their antioxidant capabilities. An impressive amount of basic science and clinical research has been conducted in both an attempt to discover novel strategies for preventing detrimental sun damage and to validate the addition of vitamins to skin care products. As dermatologists, it will be essential to provide our patients with substantiated counseling regarding the efficacy of commercial assertions. In this review, we will systematically examine the evidence supporting the use of vitamins in oral and topical formulations and provide a brief summary of the pathogenesis of photoaging. Limitations of this study include that there may be unpublished data or additional studies that may have been overlooked in our comprehensive review of this topic.
随着化妆品行业的兴起，许多声称能减少光老化临床表现的配方产品纷纷涌现。这些产品中的许多都利用了公众与维生素的积极联系，尤其是它们的抗氧化能力。人们已经进行了大量的基础科学和临床研究，试图寻找预防有害阳光损伤的新策略，并验证将维生素添加到护肤品中的效果。作为皮肤科医生，为患者提供有关商业主张有效性的合理建议将至关重要。在这篇综述中，我们将系统地检查支持口服和局部制剂中使用维生素的证据，并简要总结光老化的发病机制。本研究的局限性包括可能存在未发表的数据或我们对该主题进行全面审查时可能忽略的其他研究。
