Northern General Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Herries Road, Sheffield, UK.
Age Ageing. 2010 May;39(3):289-94. doi: 10.1093/ageing/afq009. Epub 2010 Feb 26.
The number of older people living with human immunodeficiency virus (HIV) in the UK is rising. Older people are at risk of acquiring HIV infection for a multitude of reasons. This, combined with effective HIV treatment which has significantly prolonged life expectancy, means that health care professionals working in the UK can expect to see increasing numbers of older people with HIV infection. In this review article, we summarise the epidemiology of HIV amongst older people, including data from our local cohort in the city of Sheffield, UK. We discuss specific and practical issues in older patients including why older people are at risk, how to make a diagnosis and the importance of doing so early, guidelines for HIV testing and an update on anti-retroviral therapy including drug interactions and side effects.
在英国，感染人类免疫缺陷病毒 (HIV) 的老年人数量正在上升。老年人由于多种原因面临感染 HIV 的风险。再加上有效的 HIV 治疗大大延长了预期寿命，这意味着在英国工作的医疗保健专业人员预计会看到越来越多的感染 HIV 的老年人。在这篇综述文章中，我们总结了 HIV 在老年人中的流行病学情况，包括来自我们在英国谢菲尔德市的本地队列的数据。我们讨论了老年患者的具体和实际问题，包括为什么老年人处于危险之中，如何做出诊断以及早期诊断的重要性，HIV 检测指南以及抗逆转录病毒治疗的最新进展，包括药物相互作用和副作用。
