Fleiszig Suzanne M J, Evans David J
School of Optometry and Graduate Programs in Vision Science, Microbiology, Infectious Disease and Immunity, and Health and Medical Sciences, University of California-Berkeley, Berkeley, CA, USA.
Optom Vis Sci. 2010 Apr;87(4):225-32. doi: 10.1097/OPX.0b013e3181d408ee.
Sight-threatening microbial keratitis associated with contact lens wear remains a serious concern for patients, eye-care practitioners, and the contact lens industry. Several decades of research and some major advances in lens and solution technology have not resulted in a decline in disease incidence. Here, we offer a perspective on the complex pathogenesis of microbial keratitis, the factors that have prevented a better understanding of this disease, and new approaches being used to tackle this important clinical problem.
与隐形眼镜佩戴相关的威胁视力的微生物性角膜炎,仍然是患者、眼科护理从业者以及隐形眼镜行业严重关切的问题。数十年的研究以及镜片和护理液技术的一些重大进展,并未使该疾病的发病率下降。在此,我们就微生物性角膜炎的复杂发病机制、阻碍对该疾病深入了解的因素,以及用于解决这一重要临床问题的新方法提供一种观点。