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液相色谱-质谱联用中峰检测算法的综述。

Review of peak detection algorithms in liquid-chromatography-mass spectrometry.

机构信息

Dept. of ECE, University of Texas at San Antonio, San Antonio, TX 78249, USA.

出版信息

Curr Genomics. 2009 Sep;10(6):388-401. doi: 10.2174/138920209789177638.

DOI:10.2174/138920209789177638
PMID:20190954
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2766790/
Abstract

In this review, we will discuss peak detection in Liquid-Chromatography-Mass Spectrometry (LC/MS) from a signal processing perspective. A brief introduction to LC/MS is followed by a description of the major processing steps in LC/MS. Specifically, the problem of peak detection is formulated and various peak detection algorithms are described and compared.

摘要

在这篇综述中，我们将从信号处理的角度讨论液相色谱-质谱联用（LC/MS）中的峰检测。简要介绍 LC/MS 后，描述了 LC/MS 的主要处理步骤。具体来说，我们对峰检测问题进行了公式化，并描述和比较了各种峰检测算法。

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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9de/2766790/a10d5afd0092/CG-10-388_F8.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9de/2766790/631ad5d93dec/CG-10-388_F12.jpg

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