Department of Orthopedic Surgery, Cheju National University Hospital, Jeju, Korea.
Clin Orthop Surg. 2010 Mar;2(1):59-62. doi: 10.4055/cios.2010.2.1.59. Epub 2010 Feb 4.
Hansenula anomala (H. anomaly) is part of the normal flora in the alimentary tract and throat. It has been reported to be an organism causing opportunistic infections in immunocompromised patients. However, cases of fungal arthritis caused by H. anomala are rare. We encountered a case of H. anomala arthritis in a 70-year-old man who was treated with an empirical antibiotic treatment and surgery under the impression of septic arthritis. However, the patient did not improve after antibiotic therapy and surgery. Consequently, knee joint aspiration was performed again, which identified fungal arthritis caused by H. anomala. It was treated successfully with amphotericin B and fluconazole. When treating arthritis patients with diabetes, it is important to consider the possibility of septic arthritis by H. anomala and provide the appropriate treatment.
异常汉逊酵母（H. anomaly）是消化道和喉咙正常菌群的一部分。它已被报道为免疫功能低下患者机会性感染的病原体。然而，由异常汉逊酵母引起的真菌性关节炎病例较为罕见。我们遇到一例 70 岁男性的异常汉逊酵母关节炎病例，该患者曾接受经验性抗生素治疗和手术治疗，印象为化脓性关节炎。然而，患者在抗生素治疗和手术后并未改善。因此，再次进行膝关节抽吸，鉴定为异常汉逊酵母引起的真菌性关节炎。使用两性霉素 B 和氟康唑成功治疗。治疗糖尿病性关节炎患者时，重要的是要考虑到异常汉逊酵母引起的化脓性关节炎的可能性，并提供适当的治疗。
