Le Moing G, Gendrel D, Couvreur J, Gaultier C, Tournier G, Gerbeaux J
Nouv Presse Med. 1977 Dec 3;6(41):3825-33.
Four children aged between 7 and 19 months with severe bronchopneumonia due to adenovirus type 7, proved by virology and/or serology developed severe hyponatraemia. One of them is reported in detail: it was possible to estimate plasma ADH levels and thereby prove the existence of reversible hypersecretion of the hormone. Whilst the syndrome of hyponatraemia with inappropriate secretion of ADH has not yet been reported in association with severe pneumonia in the child, it is known in adults. The limits of the syndrome and its physiopathology are discussed. It may be due either to vagal stimulation as a result of a fall in left aressure, or to central involvement. Therapeutic implications of the problem are emphasized.
4名年龄在7至19个月之间的儿童因7型腺病毒感染患上严重支气管肺炎，经病毒学和/或血清学证实，他们出现了严重低钠血症。其中一名儿童的情况被详细报道：可以估计血浆抗利尿激素（ADH）水平，从而证实该激素存在可逆性分泌过多。虽然儿童严重肺炎相关的抗利尿激素分泌不当所致低钠血症综合征尚未见报道，但在成人中是已知的。本文讨论了该综合征的界限及其病理生理学。它可能是由于左心房压力下降导致迷走神经刺激，也可能是中枢受累所致。强调了该问题的治疗意义。
