Moore M C, Thompson C W, Marler C A
Department of Zoology, Arizona State University, Tempe 85287.
Gen Comp Endocrinol. 1991 Feb;81(2):217-26. doi: 10.1016/0016-6480(91)90006-r.
To examine the reciprocal interactions among gonadal and adrenal steroid secretion, male tree lizards (Urosaurus ornatus) were subjected to two forms of stress. They were subjected either to the acute stress of being held in collecting bags for up to 4 hr or to the chronic stress of being maintained in individual cages in the laboratory for up to 3 weeks. In both cases, levels in stressed animals were compared to levels in free-living animals as controls. Under both conditions plasma levels of corticosterone increased and plasma levels of testosterone decreased compared to free-living controls. The response to the acute stress was much greater for both hormones than to the chronic stress, although in both cases testosterone levels changed less in response to stress than corticosterone levels. The corticosterone response to acute stress was extremely rapid with levels increasing over six-fold in the first 10 min. Plasma levels of corticosterone and testosterone were negatively correlated among individuals in the chronic stress experiment, but not in the acute stress experiment. This correlational evidence is consistent with the hypothesis of a direct effect of corticosterone levels on testosterone levels and suggests that these may only be expressed under some conditions.
为了研究性腺和肾上腺类固醇分泌之间的相互作用，雄性丽纹龙蜥（Urosaurus ornatus）接受了两种形式的应激。它们要么承受被装在收集袋中长达4小时的急性应激，要么承受在实验室单独笼子里饲养长达3周的慢性应激。在这两种情况下，将应激动物的水平与作为对照的自由生活动物的水平进行比较。与自由生活的对照相比，在两种条件下，血浆皮质酮水平均升高，而血浆睾酮水平均降低。两种激素对急性应激的反应比对慢性应激的反应要大得多，尽管在两种情况下，睾酮水平对应激的变化都小于皮质酮水平。皮质酮对急性应激的反应极其迅速，在最初10分钟内水平增加了六倍多。在慢性应激实验中，个体之间血浆皮质酮和睾酮水平呈负相关，但在急性应激实验中并非如此。这种相关性证据与皮质酮水平对睾酮水平有直接影响的假设一致，并表明这些影响可能仅在某些条件下才会表现出来。
