Department of Cataract Surgery and Refractive Surgery, University of São Paulo, São Paulo, Brazil.
Indian J Ophthalmol. 2010 Mar-Apr;58(2):109-13. doi: 10.4103/0301-4738.60075.
To evaluate wavefront performance and modulation transfer function (MTF) in the human eye after the implantation of diffractive or refractive multifocal intraocular lenses (IOLs).
This was a prospective, interventional, comparative, nonrandomized clinical study. Uncorrected distance and near visual acuity, and wavefront analysis including MTF curves (iTrace aberrometer, Tracey Technologies, Houston, TX, USA) were measured in 60 patients after bilateral IOL implantation with 6 months of follow-up. Forty eyes received the diffractive ReSTOR (Alcon), 40 eyes received the refractive ReZoom (Advanced Medical Optics) and 40 eyes, the Tecnis ZM900 (Advanced Medical Optics). The comparison of MTF and aberration between the intraocular lenses was performed using analysis of variance (ANOVA), followed by the Dunn test when necessary.
The mean uncorrected distance visual acuity was similar in all three groups of multifocal IOLs. The ReSTOR group provided better uncorrected near visual acuity than the ReZoom group (P<0.001), but similar to the Tecnis group. Spherical aberration was significantly higher in the ReZoom group (P=0.007). Similar MTF curves were found for the aspheric multifocal IOL Tecnis and the spheric multifocal IOL ReSTOR, and both performed better than the multifocal IOL ReZoom in a 5 mm pupil (P<0.001 at all spatial frequencies).
Diffractive IOLs studied presented similar MTF curves for a 5 mm pupil diameter. Both diffractive IOLs showed similar spherical aberration, which was significantly better with the full-diffractive IOL Tecnis than with the refractive IOL ReZoom.
评估人眼在植入衍射或折射多焦点人工晶状体（IOL）后波前性能和调制传递函数（MTF）。
这是一项前瞻性、干预性、对比性、非随机的临床研究。60 例患者接受双侧 IOL 植入术后 6 个月，进行了未矫正的远距和近距视力以及波前分析，包括 MTF 曲线（iTrace 像差仪，Tracey Technologies，休斯顿，TX，美国）。40 只眼植入衍射型 ReSTOR（爱尔康），40 只眼植入折射型 ReZoom（先进医疗光学），40 只眼植入 Tecnis ZM900（先进医疗光学）。使用方差分析（ANOVA）比较人工晶状体之间的 MTF 和像差，必要时使用 Dunn 检验。
三组多焦点 IOL 的平均未矫正远视力相似。ReSTOR 组的未矫正近视力优于 ReZoom 组（P<0.001），但与 Tecnis 组相似。ReZoom 组的球差明显较高（P=0.007）。Tecnis 非球面多焦点 IOL 和 ReSTOR 球面多焦点 IOL 的 MTF 曲线相似，两者在 5mm 瞳孔下的性能均优于 ReZoom 多焦点 IOL（所有空间频率下 P<0.001）。
研究的衍射型 IOL 具有相似的 5mm 瞳孔直径 MTF 曲线。两种衍射型 IOL 的球差相似，全衍射型 IOL Tecnis 的球差明显优于折射型 IOL ReZoom。
