Lee Chong-Suh, Chung Sung Soo, Choi Sung Woo, Yu Jae Wook, Sohn Min Su
From the Department of Orthopedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Spine (Phila Pa 1976). 2010 Mar 15;35(6):E206-11. doi: 10.1097/BRS.0b013e3181bfa518.
A retrospective study.
To determine the critical length of fusion that warrants additional stronger fixation in lumbosacral (L-S) fusion, and to analyze the risk factors of nonunion at the L-S junction.
Long lever arm fusion down to S1 requires stronger fixation than short lever arm fusion. However, no published criteria are available about the critical length of fusion requiring stronger fixation to the ilium or S2 to obtain adequate stability for union at the L-S junction.
A total of 327 adult patients with degenerative lumbar disease, who were treated with instrumented fusion, including the L-S junction, were included in this study. Mean patient age was 59.7 (20-79) years and the minimum follow-up was 12 months. Union rates were compared using univariate and multivariate logistic regression analysis. Length of fusion, age, sex, lumbar lordosis at preoperative, early postoperative and final follow-ups, BMD, smoking history, associated morbidities, fat content of paraspinal muscle, methods of fusion, and levels of intercristal line were examined as independent variables to identify factors that affect union rate at the L-S junction.
Of the 327 patients, 47 (14.4%) had nonunion at the L-S junction. Union rate of the L-S junction at the single level, and at 2, 3, 4, 5, and more than 5 levels were 96.6%, 92.9%, 87.4%, 64.7%, 66.7%, and 58.0%, respectively. A significant difference of union rate was found between less than 4 levels and 4 or more levels of fusion (P < 0.05). The factors found by multivariate analysis to significantly affect union rate at the L-S junction were fusion length and fat content of paraspinal muscle.
The risk of nonunion at the L-S junction was found to increase significantly for more than 3 levels of fusion. We advise that additional stronger fixation is needed in such cases.
一项回顾性研究。
确定腰骶(L-S)融合术中保证额外更强固定所需的关键融合长度,并分析L-S节段不愈合的危险因素。
长杠杆臂融合至S1需要比短杠杆臂融合更强的固定。然而,关于需要向髂骨或S2进行更强固定以在L-S节段获得足够稳定性以实现愈合的关键融合长度,尚无已发表的标准。
本研究纳入了327例接受包括L-S节段在内的器械融合治疗的成年退行性腰椎疾病患者。患者平均年龄为59.7(20 - 79)岁,最短随访时间为12个月。使用单因素和多因素逻辑回归分析比较融合率。将融合长度、年龄、性别、术前、术后早期和最终随访时的腰椎前凸、骨密度、吸烟史、相关合并症、椎旁肌脂肪含量、融合方法以及髂嵴连线水平作为自变量进行检查,以确定影响L-S节段融合率的因素。
327例患者中,47例(14.4%)在L-S节段出现不愈合。单节段、2节段、3节段、4节段、5节段及超过5节段的L-S节段融合率分别为96.6%、92.9%、87.4%、64.7%、66.7%和58.0%。发现融合少于4节段与4节段或更多节段之间的融合率存在显著差异(P < 0.05)。多因素分析发现显著影响L-S节段融合率的因素是融合长度和椎旁肌脂肪含量。
发现L-S节段融合超过3节段时不愈合风险显著增加。我们建议在这种情况下需要额外更强的固定。