Unit of Vector Biology & Control, Department of Environmental Health Science, College of Public Health & Medical Sciences, Jimma University, Jimma, Ethiopia.
Parasitol Res. 2010 Apr;106(5):1217-23. doi: 10.1007/s00436-010-1797-y. Epub 2010 Mar 2.
A laboratory study was carried out to evaluate the repellent efficacy of a methanol-leaf extract of Ethiopian traditionally used insect repellent plant viz., Lomi sar [vernacular name (local native language, Amharic); Cymbopogon citratus (DC) Stapf. (Poaceae)] against Anopheles arabiensis at four different concentrations viz., 1.0, 1.5, 2.0, and 2.5 mg/cm(2). The percentage protection in relation to the dose method was performed. C. citratus extract has shown various degrees of repellency impact against A. arabiensis. It provided the maximum total percentage protection of 78.83% at 2.5 mg/cm(2) and followed 68.06% at 2.0 mg/cm(2) for 12 h. All four tested concentrations of C. citratus extract offered significant protection and Student's t test results shows statistically significant (p value = 0.001) [1.0 mg/cm(2) (t = 22.89; df = 4); 1.5 mg/cm(2) (t = 24.03; df = 4); 2.0 mg/cm(2) (t = 36.92; df = 4); 2.5 mg/cm(2) (t = 22.31; df = 4)] difference between treated and control groups. The result suggests that it could serve as a potent insect repellent against vectors of disease. Globally, C. citratus is renowned for its therapeutic values. Above and beyond, due to its user- as well as environmental-friendly nature, it should be promoted among the marginalized populations in order to reduce man-vector contact. In addition, this appropriate strategy affords the opportunity to minimize chemical repellent usage and the risks associated with adverse side effects. At the end of the day, traditionally used plant-based insect repellents could be viable safer alternative sources for chemical insect repellents.
进行了一项实验室研究，以评估甲醇叶提取物对埃塞俄比亚传统驱虫植物 Lomi sar（当地土语，即 Amharic；Cymbopogon citratus (DC) Stapf.（禾本科））的驱虫功效，针对 Anopheles arabiensis，测试了 4 个不同浓度，分别为 1.0、1.5、2.0 和 2.5mg/cm(2)。采用剂量法计算了保护率。C. citratus 提取物对 A. arabiensis 表现出不同程度的驱避作用。在 2.5mg/cm(2)时，它提供了最大的总保护率 78.83%，在 2.0mg/cm(2)时为 68.06%，持续 12 小时。C. citratus 提取物的 4 个测试浓度均提供了显著的保护作用，学生 t 检验结果显示具有统计学意义（p 值=0.001）[1.0mg/cm(2)（t=22.89；df=4）；1.5mg/cm(2)（t=24.03；df=4）；2.0mg/cm(2)（t=36.92；df=4）；2.5mg/cm(2)（t=22.31；df=4）]，处理组和对照组之间存在差异。结果表明，它可以作为一种有效的疾病传播媒介驱虫剂。全球范围内，C. citratus 因其治疗价值而闻名。除此之外，由于其对用户和环境友好的特性，应在边缘人群中推广，以减少人与媒介的接触。此外，这种适当的策略为减少化学驱虫剂的使用和与不良副作用相关的风险提供了机会。归根结底，传统的植物源驱虫剂可以作为化学驱虫剂的可行替代品。
