• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

开发一种更聚焦的磁刺激器。第一部分:一些基本原理。

Developing a more focal magnetic stimulator. Part I: Some basic principles.

作者信息

Cohen D, Cuffin B N

机构信息

Francis Bitter National Magnet Laboratory, Massachusetts Institute of Technology, Cambridge 02139.

出版信息

J Clin Neurophysiol. 1991 Jan;8(1):102-11. doi: 10.1097/00004691-199101000-00013.

DOI:10.1097/00004691-199101000-00013
PMID:2019645
Abstract

Some general properties of currents induced by magnetic stimulators in volume conductors of any shape are first reviewed. Then, the property of focality (concentration at some internal point) of the current induced in a spherical model of the head is discussed, due to coils of various orientations and configurations. It is shown that one important property for focality is the complete absence of the radial component of current, regardless of the coil used. The theoretically computed current distributions in the sphere produced by three different coils are illustrated. These are (1) a circular coil parallel to the head (very nonfocal). (2) a circular coil erect on the head (more focal), and (3) a figure-eight coil parallel to the head (most focal). A computational search for yet more focal coil configurations shows that the figure-eight focality can only be altered somewhat, but basically not improved. A plot of focality of the figure-eight coil versus the diameter of its coils shows an improvement in focality with decreasing diameter down to one cm. At this diameter, the induced current at a level 2 cm below the coil is concentrated in a band 1.5 cm wide (half-maximum points). Finally, it is noted that as the diameter of the figure-eight coil is decreased, the current in the coil necessary for stimulation increases rapidly, with increasing engineering problems.

摘要

首先回顾一下磁刺激器在任意形状的体导体中所感应电流的一些一般特性。然后,讨论在头部球形模型中,由于各种取向和配置的线圈所感应电流的聚焦特性(集中在某个内部点)。结果表明,对于聚焦而言,一个重要特性是无论使用何种线圈,电流的径向分量完全不存在。文中展示了由三种不同线圈在球体中理论计算出的电流分布。它们分别是:(1)与头部平行的圆形线圈(非常不聚焦);(2)直立在头部的圆形线圈(更聚焦);(3)与头部平行的8字形线圈(最聚焦)。对更聚焦的线圈配置进行计算搜索表明,8字形的聚焦性只能有所改变,但基本上无法得到改善。8字形线圈的聚焦性与其线圈直径的关系图显示,随着直径减小到1厘米,聚焦性有所提高。在此直径下,线圈下方2厘米处的感应电流集中在一个1.5厘米宽的带内(半最大值点)。最后需要注意的是,随着8字形线圈直径的减小,刺激所需的线圈电流会迅速增加,工程问题也会随之增加。

相似文献

1
Developing a more focal magnetic stimulator. Part I: Some basic principles.开发一种更聚焦的磁刺激器。第一部分:一些基本原理。
J Clin Neurophysiol. 1991 Jan;8(1):102-11. doi: 10.1097/00004691-199101000-00013.
2
Developing a more focal magnetic stimulator. Part II: Fabricating coils and measuring induced current distributions.开发一种更聚焦的磁刺激器。第二部分:制造线圈并测量感应电流分布。
J Clin Neurophysiol. 1991 Jan;8(1):112-20.
3
Electric field depth-focality tradeoff in transcranial magnetic stimulation: simulation comparison of 50 coil designs.经颅磁刺激中的电场深度-聚焦权衡:50 种线圈设计的模拟比较。
Brain Stimul. 2013 Jan;6(1):1-13. doi: 10.1016/j.brs.2012.02.005. Epub 2012 Mar 21.
4
Electric field properties of two commercial figure-8 coils in TMS: calculation of focality and efficiency.经颅磁刺激中两种商用8字形线圈的电场特性:聚焦性和效率的计算
Clin Neurophysiol. 2004 Jul;115(7):1697-708. doi: 10.1016/j.clinph.2004.02.019.
5
H-coil: Induced electric field properties and input/output curves on healthy volunteers, comparison with a standard figure-of-eight coil.H型线圈:健康志愿者的感应电场特性及输入/输出曲线,与标准8字形线圈的比较
Clin Neurophysiol. 2009 Jun;120(6):1174-82. doi: 10.1016/j.clinph.2009.02.176. Epub 2009 May 9.
6
Design of transcranial magnetic stimulation coils with optimal trade-off between depth, focality, and energy.设计一种经颅磁刺激线圈,在深度、聚焦性和能量之间达到最佳折衷。
J Neural Eng. 2018 Aug;15(4):046033. doi: 10.1088/1741-2552/aac967. Epub 2018 Jun 1.
7
Comprehensive Survey on Improved Focality and Penetration Depth of Transcranial Magnetic Stimulation Employing Multi-Coil Arrays.关于采用多线圈阵列提高经颅磁刺激的聚焦性和穿透深度的综合研究
Int J Environ Res Public Health. 2017 Nov 14;14(11):1388. doi: 10.3390/ijerph14111388.
8
Technical and practical aspects of magnetic nerve stimulation.磁神经刺激的技术与实践方面
J Clin Neurophysiol. 1991 Jan;8(1):10-25. doi: 10.1097/00004691-199101000-00004.
9
Minimum-energy coils for transcranial magnetic stimulation: application to focal stimulation.用于经颅磁刺激的最小能量线圈:在聚焦刺激中的应用。
Brain Stimul. 2015 Jan-Feb;8(1):124-34. doi: 10.1016/j.brs.2014.10.002. Epub 2014 Oct 13.
10
Frequency-related effects in the optimization of coils for the magnetic stimulation of the nervous system.用于神经系统磁刺激的线圈优化中的频率相关效应。
IEEE Trans Biomed Eng. 2002 May;49(5):463-71. doi: 10.1109/10.995685.

引用本文的文献

1
State-Dependent Transcranial Magnetic Stimulation Synchronized with Electroencephalography: Mechanisms, Applications, and Future Directions.与脑电图同步的状态依赖性经颅磁刺激:机制、应用及未来方向
Brain Sci. 2025 Jul 8;15(7):731. doi: 10.3390/brainsci15070731.
2
A cell type-specific mechanism driving the rapid antidepressant effects of transcranial magnetic stimulation.一种驱动经颅磁刺激快速抗抑郁作用的细胞类型特异性机制。
bioRxiv. 2025 Jan 30:2025.01.29.635537. doi: 10.1101/2025.01.29.635537.
3
Microfabrication Technologies for Nanoinvasive and High-Resolution Magnetic Neuromodulation.
用于纳米侵入性和高分辨率磁神经调节的微制造技术
Adv Sci (Weinh). 2024 Dec;11(46):e2404254. doi: 10.1002/advs.202404254. Epub 2024 Oct 24.
4
Repetitive peripheral magnetic stimulation for preventing shoulder subluxation after stroke: a randomized controlled trial.重复经颅磁刺激预防脑卒中后肩关节半脱位的随机对照研究
Eur J Phys Rehabil Med. 2024 Apr;60(2):216-224. doi: 10.23736/S1973-9087.24.08264-9. Epub 2024 Mar 14.
5
Shielded Cone Coil Array for Non-Invasive Deep Brain Magnetic Stimulation.屏蔽锥形线圈阵列用于非侵入性脑深部磁刺激。
Biosensors (Basel). 2024 Jan 9;14(1):32. doi: 10.3390/bios14010032.
6
High inductance magnetic-core coils have enhanced efficiency in inducing suprathreshold motor response in rats.高感磁芯线圈在诱导大鼠超阈值运动反应方面具有更高的效率。
Phys Med Biol. 2023 Dec 8;68(24). doi: 10.1088/1361-6560/ad0bde.
7
High-Performance Magnetic-core Coils for Targeted Rodent Brain Stimulations.用于靶向啮齿动物脑刺激的高性能磁芯线圈。
BME Front. 2022 Mar 5;2022:9854846. doi: 10.34133/2022/9854846. eCollection 2022.
8
Design and evaluation of a rodent-specific focal transcranial magnetic stimulation coil with the custom shielding application in rats.一种用于大鼠的定制屏蔽应用的啮齿动物专用聚焦经颅磁刺激线圈的设计与评估。
Front Neurosci. 2023 Apr 17;17:1129590. doi: 10.3389/fnins.2023.1129590. eCollection 2023.
9
Development and application of rTMS device to murine model.rTMS 设备在鼠模型中的开发与应用。
Sci Rep. 2023 Apr 4;13(1):5490. doi: 10.1038/s41598-023-32646-w.
10
A C-shaped miniaturized coil for transcranial magnetic stimulation in rodents.一种用于啮齿动物经颅磁刺激的 C 形微型线圈。
J Neural Eng. 2023 Mar 24;20(2):026022. doi: 10.1088/1741-2552/acc097.