Nasr Suhayl, Wendt Burdette, Kora Shilpa
Nasr Psychiatric Services, 2814 South Franklin Street, Michigan City, IN 46360, USA.
Ann Clin Psychiatry. 2010 Feb;22(1):29-32.
The rate of mood disorders in patients in sleep centers has been the subject of many studies, yet little has been published on the incidence of sleep apnea in psychiatric patients.
A retrospective chart review was performed on 330 consecutively seen psychiatric outpatients. Medication history, demographics, and the results of patients' most recent Quick Inventory of Depressive Symptomatology (QIDS) were collected. Patients were checked for a history of apnea through a review of session notes and the results of any polysomnogram that the patient had on file.
Of the patients studied, 9.7% were positive for sleep apnea. They required a significantly higher number of medications (3.2 vs 2.4; P < .001). They also scored significantly higher on 3 items on the QIDS: late insomnia (1.0 vs 0.55; P < .01), reduced energy level (1.2 vs 0.76; P < .02), and decreased general interest (1.0 vs 0.64; P < .04). Middle age in men (age 45 to 64) and higher body mass index both in men and women were also associated with a higher frequency of sleep apnea.
Sleep apnea is more prevalent in psychiatric outpatients than in the general population. Identification of this comorbid condition will likely result in better treatment outcomes.
睡眠中心患者的情绪障碍发生率一直是许多研究的主题，但关于精神科患者睡眠呼吸暂停发生率的报道却很少。
对330例连续就诊的精神科门诊患者进行回顾性病历审查。收集用药史、人口统计学资料以及患者最近的抑郁症状快速量表（QIDS）结果。通过查阅病历记录和患者存档的多导睡眠图结果，检查患者是否有呼吸暂停病史。
在研究的患者中，9.7%的患者睡眠呼吸暂停呈阳性。他们需要服用的药物数量明显更多（3.2 比 2.4；P < .001）。他们在QIDS的3项指标上得分也明显更高：晚期失眠（1.0 比 0.55；P < .01）、精力水平降低（1.2 比 0.76；P < .02）以及总体兴趣下降（1.0 比 0.64；P < .04）。男性中年（45至64岁）以及男性和女性较高的体重指数也与较高的睡眠呼吸暂停发生率相关。
睡眠呼吸暂停在精神科门诊患者中比在普通人群中更普遍。识别这种合并症可能会带来更好的治疗效果。
