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BMJ Case Rep. 2018 Jul 10;2018:bcr-2018-224873. doi: 10.1136/bcr-2018-224873.
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本文引用的文献

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Anxiety and depression are improved by continuous positive airway pressure treatments in obstructive sleep apnea.阻塞性睡眠呼吸暂停患者通过持续气道正压治疗后,焦虑和抑郁症状得到改善。
Int J Psychiatry Med. 2016 Aug;51(6):554-562. doi: 10.1177/0091217417696737. Epub 2017 Mar 6.
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Risk of obstructive sleep apnea and excessive daytime sleepiness in hospitalized psychiatric patients.住院精神科患者阻塞性睡眠呼吸暂停及日间过度嗜睡的风险
Neuropsychiatr Dis Treat. 2017 Apr 26;13:1193-1200. doi: 10.2147/NDT.S131311. eCollection 2017.
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Cooccurrence and bidirectional prediction of sleep disturbances and depression in older adults: Meta-analysis and systematic review.老年人睡眠障碍与抑郁共病及双向预测:荟萃分析与系统综述。
Neurosci Biobehav Rev. 2017 Apr;75:257-273. doi: 10.1016/j.neubiorev.2017.01.032. Epub 2017 Feb 6.
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Bidirectional association between obstructive sleep apnea and depression: A population-based longitudinal study.阻塞性睡眠呼吸暂停与抑郁症之间的双向关联:一项基于人群的纵向研究。
Medicine (Baltimore). 2016 Sep;95(37):e4833. doi: 10.1097/MD.0000000000004833.
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The prevalence and predictors of obstructive sleep apnea in major depressive disorder, bipolar disorder and schizophrenia: A systematic review and meta-analysis.重度抑郁症、双相情感障碍和精神分裂症中阻塞性睡眠呼吸暂停的患病率及预测因素:一项系统评价和荟萃分析。
J Affect Disord. 2016 Jun;197:259-67. doi: 10.1016/j.jad.2016.02.060. Epub 2016 Mar 9.
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Depressive Symptoms before and after Treatment of Obstructive Sleep Apnea in Men and Women.男性和女性阻塞性睡眠呼吸暂停治疗前后的抑郁症状
J Clin Sleep Med. 2015 Sep 15;11(9):1029-38. doi: 10.5664/jcsm.5020.
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Obstructive sleep apnea and psychiatric disorders: a systematic review.阻塞性睡眠呼吸暂停与精神障碍:一项系统综述
J Clin Sleep Med. 2015 Jan 15;11(2):165-75. doi: 10.5664/jcsm.4466.
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An official American Thoracic Society Clinical Practice Guideline: sleep apnea, sleepiness, and driving risk in noncommercial drivers. An update of a 1994 Statement.美国胸科学会临床实践指南:非商业驾驶员的睡眠呼吸暂停、嗜睡与驾驶风险。对 1994 年声明的更新。
Am J Respir Crit Care Med. 2013 Jun 1;187(11):1259-66. doi: 10.1164/rccm.201304-0726ST.
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Obstructive sleep apnea and the subsequent risk of depressive disorder: a population-based follow-up study.阻塞性睡眠呼吸暂停及随后抑郁障碍的风险:一项基于人群的随访研究。
J Clin Sleep Med. 2013 May 15;9(5):417-23. doi: 10.5664/jcsm.2652.
10
Sleep-disordered breathing: effects on brain structure and function.睡眠呼吸紊乱:对大脑结构和功能的影响。
Respir Physiol Neurobiol. 2013 Sep 15;188(3):383-91. doi: 10.1016/j.resp.2013.04.021. Epub 2013 May 1.

当抑郁症患者感到困倦时,要留意睡眠呼吸暂停。

When a patient with depression is feeling sleepy, be aware of sleep apnoea.

作者信息

Wiersema Carlijn, Van Zelst Willeke, Oude Voshaar Richard

机构信息

University Center for Psychiatry, University Medical Center Groningen, Groningen, The Netherlands.

出版信息

BMJ Case Rep. 2018 Jul 10;2018:bcr-2018-224873. doi: 10.1136/bcr-2018-224873.

DOI:10.1136/bcr-2018-224873
PMID:29991545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6058169/
Abstract

A 67-year-old man was referred to an outpatient clinic of geriatric psychiatry because of persistent symptoms of depression and anxiety, accompanied by sleepiness. The latter had been evaluated multiple times in the general practice over several years; each time it was considered to be a symptom of depression. After referral, the patient was diagnosed with severe obstructive sleep apnoea (OSA), comorbid to a depressive and anxiety disorder. Retrospectively, we conclude that affective symptoms accompanying OSA and sleepiness were wrongfully interpreted as depression, but after having led to problems at work, they have triggered psychiatric comorbidity. Treatment of OSA in addition to the psychiatric disorders resulted in a full recovery over time. The delayed diagnosis of OSA has certainly diminished the patient's quality of life and might have precipitated the depressive disorder. Moreover, OSA poses patients at an increased risk of cardiovascular disease, hypertension, stroke and traffic accidents.

摘要

一名67岁男性因持续存在的抑郁和焦虑症状并伴有嗜睡被转诊至老年精神病学门诊。多年来,后者在全科医疗中已被多次评估;每次都被认为是抑郁症的症状。转诊后,患者被诊断为重度阻塞性睡眠呼吸暂停(OSA),合并抑郁和焦虑障碍。回顾性地看,我们得出结论,OSA和嗜睡伴随的情感症状被错误地解释为抑郁症,但在导致工作出现问题后,引发了精神疾病共病。除精神疾病外,对OSA的治疗随着时间推移使患者完全康复。OSA的延迟诊断肯定降低了患者的生活质量,可能还促使了抑郁症的发生。此外,OSA使患者患心血管疾病、高血压、中风和交通事故的风险增加。