MIC数据库：来自文献的抗菌化合物集合。

MIC database: a collection of antimicrobial compounds from literature.

作者信息

Babu Padavala Ajay, Kumar Palakeerthi Srinivas, Padmaja Polumati, Roa T Khageswara, Chitti Sashikanth

机构信息

Translational Research Institute of Molecular Sciences (TRIMS), Bioinformatics Division, 2-35-72, MVP Colony, Sector-10, Visakhapatnam - 530017, India.

出版信息

Bioinformation. 2009 Sep 5;4(2):75-7. doi: 10.6026/97320630004075.

DOI:10.6026/97320630004075

PMID:20198173

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2823385/

Abstract

We describe a database named MIC database containing 2-dimensional structures of synthesized compounds/antibiotics, IUPAC name, smiles notation and the MIC values / zone of inhibition against a particular organism, strain and culture conditions. The data was collected from various literature sources such as Arkivoc, Bioorganic Medicinal Chemistry Letters, Antimicrobial Agents and Chemotherapy, Journal of Clinical Microbiology and Journal of Bacteriology. MIC Database can be accessed at www.trimslabs.com/mic/index.htm.

摘要

我们描述了一个名为MIC数据库的数据库，其中包含合成化合物/抗生素的二维结构、国际纯粹与应用化学联合会（IUPAC）名称、SMILES符号以及针对特定生物体、菌株和培养条件的MIC值/抑菌圈。这些数据是从各种文献来源收集的，如《天然产物全合成杂志》（Arkivoc）、《生物有机与药物化学快报》（Bioorganic Medicinal Chemistry Letters）、《抗菌药物与化疗》（Antimicrobial Agents and Chemotherapy）、《临床微生物学杂志》（Journal of Clinical Microbiology）和《细菌学杂志》（Journal of Bacteriology）。可通过www.trimslabs.com/mic/index.htm访问MIC数据库。