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通过非血红素铁加氧酶 CloR 的功能模型对α-羟基酸进行氧化脱羧。

Oxidative decarboxylation of alpha-hydroxy acids by a functional model of the nonheme iron oxygenase, CloR.

机构信息

Department of Inorganic Chemistry, Indian Association for the Cultivation of Science, 2A&2B Raja S. C. Mullick Road, Jadavpur, Kolkata-700032, India.

出版信息

Chem Commun (Camb). 2010 Mar 21;46(11):1830-2. doi: 10.1039/b925389k. Epub 2010 Feb 12.

DOI:10.1039/b925389k
PMID:20198223
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2865172/
Abstract

Iron(II)-alpha-hydroxy acid complexes of a tripodal N4 ligand undergo oxidative decarboxylation upon exposure to O(2) and mimic the aliphatic C1-C2 cleavage step catalyzed by CloR.

摘要

三齿 N4 配体的铁(II)-α-羟基酸配合物在暴露于 O(2)时会发生氧化脱羧反应，模拟 CloR 催化的脂肪族 C1-C2 断裂步骤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e46/2865172/6641b47e52ae/nihms-197337-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e46/2865172/79dd74204546/nihms-197337-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e46/2865172/ea0dea89496c/nihms-197337-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e46/2865172/892ee5a379ed/nihms-197337-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e46/2865172/8170a9c9819e/nihms-197337-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e46/2865172/6641b47e52ae/nihms-197337-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e46/2865172/79dd74204546/nihms-197337-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e46/2865172/ea0dea89496c/nihms-197337-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e46/2865172/892ee5a379ed/nihms-197337-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e46/2865172/8170a9c9819e/nihms-197337-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e46/2865172/6641b47e52ae/nihms-197337-f0005.jpg

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