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来自冲突地区的难民儿童的维生素 D 缺乏症。

Vitamin D deficiency in refugee children from conflict zones.

机构信息

University of New South Wales, Sydney, Australia.

出版信息

J Immigr Minor Health. 2011 Feb;13(1):87-93. doi: 10.1007/s10903-010-9325-9.

DOI:10.1007/s10903-010-9325-9
PMID:20198433
Abstract

Vitamin D deficiency is common in newly resettled refugee children and is associated with significant morbidity including rickets. To determine risk factors and burden of vitamin D deficiency in newly resettled refugee children in Australia. A descriptive epidemiological study and survey on refugee children attending an outpatient general health clinic at the Children's Hospital Westmead, Sydney. 215 patients were examined (age range 0-17 years), (76%) majority were from Africa. Mean serum 25OHD level was 46 nmol/L (SD = 24) (sufficiency range 50-150 nmol/L). 40% had mild deficiency (26-50 nmol/L), 19% moderate deficiency (13-25 nmol/L) and 2% were severely deficient (<13 nmol/L). Deficiency was most common in East African (72%) and Middle Eastern (66%) refugees, children in early puberty (89%) and those living in Australia >6 months (71%). Deficient children were more likely to have had movement restrictions and longer time in hiding in their country of refuge (OR 3:1[CI 0.9-9.7], P = .062).

摘要

维生素 D 缺乏症在新定居的难民儿童中很常见,与包括佝偻病在内的重大发病率有关。为了确定澳大利亚新定居难民儿童维生素 D 缺乏症的风险因素和负担。对悉尼威斯特米德儿童医院门诊普通保健诊所就诊的难民儿童进行描述性流行病学研究和调查。检查了 215 名患者(年龄 0-17 岁),(76%)多数来自非洲。平均血清 25OHD 水平为 46nmol/L(SD=24)(充足范围为 50-150nmol/L)。40%有轻度缺乏症(26-50nmol/L),19%中度缺乏症(13-25nmol/L),2%严重缺乏症(<13nmol/L)。维生素 D 缺乏症在东非(72%)和中东(66%)难民中最为常见,青春期早期的儿童(89%)和在澳大利亚生活超过 6 个月的儿童(71%)中最常见。运动受限和在避难国躲藏时间较长的儿童更有可能缺乏维生素 D(OR3:1[CI0.9-9.7],P=0.062)。

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Med J Aust. 2006;185(11-12):594-7. doi: 10.5694/j.1326-5377.2006.tb00721.x.
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Prevention and treatment of infant and childhood vitamin D deficiency in Australia and New Zealand: a consensus statement.澳大利亚和新西兰婴幼儿维生素D缺乏症的预防与治疗:共识声明
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The prevalence of vitamin D inadequacy amongst women with osteoporosis: an international epidemiological investigation.
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Int J Environ Res Public Health. 2019 Aug 10;16(16):2855. doi: 10.3390/ijerph16162855.
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Randomised Controlled Trial Comparing Daily Versus Depot Vitamin D3 Therapy in 0-16-Year-Old Newly Settled Refugees in Western Australia Over a Period of 40 Weeks.比较每日与 depot 维生素 D3 疗法在澳大利亚西部 0-16 岁新定居难民中 40 周的随机对照试验。
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"English Disease": Historical Notes on Rickets, the Bone-Lung Link and Child Neglect Issues.“英国病”:关于佝偻病、骨肺关联及儿童忽视问题的历史记录
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BMJ Open. 2016 Aug 24;6(8):e011387. doi: 10.1136/bmjopen-2016-011387.
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BMJ Open. 2015 Nov 30;5(11):e009140. doi: 10.1136/bmjopen-2015-009140.
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