Wishart H D, Reeve A M F, Grant C C
Auckland Regional Public Health Service Medical Clinic, Mangere Refugee Resettlement Centre, Manakau City, New Zealand.
Intern Med J. 2007 Dec;37(12):792-7. doi: 10.1111/j.1445-5994.2007.01385.x. Epub 2007 May 21.
Populations with increased skin pigmentation who have migrated to countries of high latitude are at increased risk of low vitamin D. This study aimed to determine the prevalence of low vitamin D among the refugee population arriving in New Zealand.
An audit of all refugees arriving at the national refugee resettlement centre from May 2004 to May 2005 was carried out. Serum 25-hydroxyvitamin D3 levels were measured and defined as normal (50-150 nmol/L) or low, with low subdivided into insufficient (25 to <50 nmol/L) and deficient (<25 nmol/L). Whether vitamin D status varied with age and sex was determined.
Vitamin D was measured in 869 (99%) of the refugees and was low in 470 (54%, 95% confidence interval (CI) 51-57%). It was insufficient in 323 (37%, 95%CI 34-41%) and deficient in 147 (17%, 95%CI 15-20%). Female sex was associated with at least a 10 times increased risk of vitamin D deficiency (relative ratio 13.93, 95%CI 10.15-17.96). Women aged between 17 and 45 years and men aged 46 years and more were at greatest risk.
Poor vitamin D status is prevalent among refugees arriving in New Zealand. Women, particularly those of child-bearing age are at greatest risk. Screening and ongoing surveillance for vitamin D deficiency should be considered for all recent refugee immigrants to New Zealand.
皮肤色素沉着增加的人群迁移至高纬度国家后，维生素D水平低的风险会增加。本研究旨在确定抵达新西兰的难民群体中维生素D水平低的患病率。
对2004年5月至2005年5月抵达国家难民安置中心的所有难民进行了一次审查。测量血清25-羟基维生素D3水平，并将其定义为正常（50-150纳摩尔/升）或低水平，低水平又细分为不足（25至<50纳摩尔/升）和缺乏（<25纳摩尔/升）。确定维生素D状态是否随年龄和性别而变化。
对869名（99%）难民进行了维生素D检测，其中470名（54%，95%置信区间（CI）51-57%）维生素D水平低。其中323名（37%，95%CI 34-41%）不足，147名（17%，95%CI 15-20%）缺乏。女性维生素D缺乏风险至少增加10倍（相对比率13.93，95%CI 10.15-17.96）。年龄在17至45岁之间的女性和46岁及以上的男性风险最大。
抵达新西兰的难民中维生素D状态不佳很普遍。女性，尤其是育龄女性风险最大。对于所有近期抵达新西兰的难民移民，应考虑进行维生素D缺乏的筛查和持续监测。
