Dimitrakova E, Pekhlivanov B, Milchev N
Akush Ginekol (Sofiia). 2009;48(4):54-5.
We report a case of uterine choriocarcinoma in a 42-year-old female presenting with abdominal pain, uterus enlargement, high serum levels of beta human chorionic gonadotropin (b-hCG) and a positive pregnancy test on two separate occasions. At laparatomy, blood and clots were observed in the abdomen, an enlarged uterus with tumor infiltrates in the uterus, appendix, bladder and plica vesico-uterina. Follwing hysterectomy and bilateral oophoorectomy, the patient received chemotherapy and was followed for two years. No tumor recurrences were observed and the b-hCG levels returned to normal. In conclusion, the condition responds favorably the chemotherapy and recurrences are rate when there are no metastases to the liver or the brain.
我们报告一例42岁女性子宫绒毛膜癌病例,该患者表现为腹痛、子宫增大、血清β-人绒毛膜促性腺激素(β-hCG)水平升高,且两次独立检测妊娠试验均为阳性。剖腹探查时,在腹腔内观察到血液和血凝块,子宫增大,肿瘤浸润子宫、阑尾、膀胱及膀胱子宫襞。子宫切除及双侧卵巢切除术后,患者接受化疗并随访两年。未观察到肿瘤复发,β-hCG水平恢复正常。总之,该疾病对化疗反应良好,在无肝或脑转移时复发率较低。