School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA.
Langmuir. 2010 Apr 6;26(7):4607-12. doi: 10.1021/la100294p.
Coupling molecular sensing with electrical conductivity may provide an important and valuable resource in assessing disease pathology. Here, we introduce pH-responsive hydrogels with homogeneously synthesized gold (Au) nanoparticles that reversibly alter conductivity through pH-induced volumetric swelling. These intelligent hybrid materials respond to physiological pH shifts (pH 7.4 to 5.5) that can (1) alter the conductivity of the gel or (2) create conductive conduits via micropatterned arrays.
将分子传感与电导率相结合，可能为评估疾病病理提供重要而有价值的资源。在这里，我们介绍了具有均匀合成金 (Au) 纳米粒子的 pH 响应水凝胶，该水凝胶通过 pH 诱导的体积膨胀可逆地改变电导率。这些智能混合材料可响应生理 pH 变化（pH 7.4 至 5.5），从而 (1) 改变凝胶的电导率，或 (2) 通过微图案化阵列创建导电通道。
