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主动脉弓部腔内修复术十年经验总结

Ten years of endovascular aortic arch repair.

机构信息

Department of Vascular Surgery, Università Vita-Salute, Scientific Institute H. San Raffaele, Via Olgettina, 60, 20132 Milan, Italy.

出版信息

J Endovasc Ther. 2010 Feb;17(1):1-11. doi: 10.1583/09-2884.1.

Abstract

PURPOSE

To evaluate a 10-year single-center experience of arch endovascular aortic repair (AEVAR) using the hybrid approach.

METHODS

Between 1999 and 2009, 311 patients were treated with endografts for thoracic aortic pathologies. The aortic arch was involved in 116 (37.3%) patients (97 men; mean age 70.3+/-10.7 years, range 27-84). There were 83 atherosclerotic aneurysms, 21 type B dissections, and 12 other lesions whose proximal landing zones were categorized according to Ishimaru's classification as 24 zone 0, 27 zone 1, and 65 zone 2. A hybrid approach was performed for all zone 0 and zone 1 procedures and in nearly half (47.7%) of zone 2 procedures. Early and midterm outcomes were reviewed retrospectively.

RESULTS

The initial clinical success in zone 0 aneurysms was 83.3%, with a 30-day mortality of 12.5% due to intraoperative stroke in all the cases. The respiratory failure rate was 12.5%, and there was 1 type I endoleak that spontaneously resolved at follow-up. Midterm clinical success at a mean 26+/-21 months was 83.3%. In zone 1 aneurysms, the initial clinical success was 82.1% without 30-day mortality or perioperative stroke. The midterm clinical success was 81.5% at a mean 21+/-17 months [2 (7.4%) late aneurysm-related deaths]. Four type I endoleaks spontaneously resolved in 3 patients. In zone 2 cases, the initial clinical success was 90.8%. There was 1 (1.5%) intraoperative death and another (1.5%) within 30 days; 1 (1.5%) patient suffered a stroke, and the respiratory and renal failure rates were 3.0%, respectively. This is the only zone in which paraplegia (2 patients, 3.0%) was encountered. The midterm clinical success was 93.9% at a mean 34+/-20 months. Four type I endoleaks spontaneously resolved in 3 patients at follow-up.

CONCLUSION

In selected patients, early and midterm outcomes of AEVAR using the hybrid approach are promising; however, mortality and morbidity, especially for zones 0 and 1, are not negligible. Our results may have practical implications for the ongoing evolution of the hybrid procedure in the aortic arch, as well as for patients fit for traditional surgery.

摘要

目的

评估 10 年单中心杂交技术在主动脉弓部腔内修复(arch endovascular aortic repair,AEVAR)中的应用经验。

方法

1999 年至 2009 年间,311 例患者因胸主动脉病变接受血管内支架植入治疗。主动脉弓部受累 116 例(37.3%)(97 例男性;平均年龄 70.3±10.7 岁,范围 27-84 岁)。其中 83 例为粥样硬化性动脉瘤,21 例为 B 型夹层,12 例其他病变,近端锚定区根据 Ishimaru 分类为 0 区 24 例,1 区 27 例,2 区 65 例。所有 0 区和 1 区病例均采用杂交技术,2 区病例近一半(47.7%)也采用杂交技术。回顾性分析早期和中期结果。

结果

0 区动脉瘤的初始临床成功率为 83.3%,30 天死亡率为 12.5%(所有病例均为术中卒中)。呼吸衰竭发生率为 12.5%,1 例 1 型内漏自行缓解。平均 26±21 个月的中期临床成功率为 83.3%。1 区动脉瘤的初始临床成功率为 82.1%,无 30 天内死亡或围手术期卒中。平均 21±17 个月的中期临床成功率为 81.5%[2 例(7.4%)迟发性动脉瘤相关死亡]。3 例患者中 4 例 1 型内漏自行缓解。2 区病例的初始临床成功率为 90.8%。术中死亡 1 例(1.5%),术后 30 天内死亡 1 例(1.5%);1 例(1.5%)患者发生卒中,呼吸和肾功能衰竭发生率分别为 3.0%。这是唯一出现截瘫(2 例,3.0%)的区域。平均 34±20 个月的中期临床成功率为 93.9%。4 例患者随访时 1 型内漏自行缓解。

结论

在选择的患者中,采用杂交技术的 AEVAR 的早期和中期结果是有希望的;然而,死亡率和发病率,特别是 0 区和 1 区,不容忽视。我们的结果可能对主动脉弓部杂交手术的不断发展以及适合传统手术的患者具有实际意义。

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