Department of Forensic Medicine, Kasturba Medical College, Mangalore 575001, India.
Singapore Med J. 2010 Jan;51(1):e15-7.
Granulomatous myocarditis is a rare disorder of the myocardium, and is usually associated with various inflammatory and autoimmune conditions. We report granulomatous myocarditis in an apparently healthy 58-year-old Indian man, who developed sudden chest pain and died while being escorted to the hospital. At the autopsy, no gross distinct cardiac lesions were observed. The histopathological sections from the left ventricular apex revealed a granuloma comprising a central area of caseous necrosis surrounded by lymphocytes, and epithelioid, plasma and Langhans giant cells. Myocardial tuberculosis was suspected as the underlying aetiology based on the histological features of the granuloma.
肉芽肿性心肌炎是一种罕见的心肌疾病,通常与各种炎症和自身免疫性疾病有关。我们报告了一例 58 岁的印度男性,他在看似健康的情况下出现了肉芽肿性心肌炎,突发胸痛,并在送往医院的途中死亡。尸检时,心脏未观察到明显的肉眼病变。左心室心尖的组织病理学切片显示一个肉芽肿,中央为干酪样坏死区,周围为淋巴细胞以及上皮样细胞、浆细胞和朗格汉斯巨细胞。根据肉芽肿的组织学特征,怀疑心肌结核是潜在的病因。