Department of Cardiothoracic Surgery, National Heart Centre, 17 Third Hospital Avenue, Singapore 168752.
Singapore Med J. 2010 Jan;51(1):69-72.
Percutaneous transcatheter implantation of the aortic valve has been demonstrated as an alternative to open heart surgery in high-risk patients with symptomatic severe aortic stenosis (AS) who are not suitable for open surgery. The majority of these new devices are delivered via the transfemoral approach. However, due to the current size of delivery sheaths, the small and tortuous iliofemoral anatomy makes this approach challenging. The transapical approach provides a viable option for this patient subgroup. The first-in-Asia transcatheter aortic valve implantation via the transapical route is described. A 79-year-old Chinese woman with symptomatic severe AS and peripheral arterial disease, who was at high surgical risk, was successfully treated, and had good functional and haemodynamic results at the three-month follow-up.
经皮经导管主动脉瓣植入术已被证明可作为高危、有症状的重度主动脉瓣狭窄（AS）且不适合开胸手术患者的一种替代治疗方法。这些新型装置多数经股动脉途径输送，但由于目前输送鞘的尺寸，以及细小迂曲的髂股动脉解剖结构，这一途径存在挑战。经心尖途径为这一患者亚组提供了一种可行的选择。本文介绍首例亚洲经心尖途径行经导管主动脉瓣植入术。一名 79 岁的中国女性，有症状的重度 AS 和外周动脉疾病，手术风险高，成功接受了治疗，在三个月随访时功能和血液动力学结果良好。
