Taşcă C, Stefăneanu L
Endocrinologie. 1977 Oct-Dec;15(4):235-41.
The authors studied the cytoenzymic pattern of various thyropathies. The highest enzymic activity was found in Graves' disease, especially for peroxidase, glucose-6-phosphate dehydrogenase and succinate dehydrogenase. Lactate dehydrogenase showed a great activity in thyroid cancer. The lowest activity was found in Hashimoto's thyroiditis with strong fibrosclerosis. The cytophotometrical data in form of histograms showed dextro-deviation of curves and plurimodal, irregular aspects of nuclear volumes and nucleic acid content in agreement with the cytological features of the investigated thyropathies. The linear regression analysis between the nuclear volumes and the nucleic acid content disclosed a diminished correlation in thyroid carcinoma and in euthyroid goitre.
作者研究了各种甲状腺疾病的细胞酶模式。在格雷夫斯病中发现酶活性最高，尤其是过氧化物酶、葡萄糖-6-磷酸脱氢酶和琥珀酸脱氢酶。乳酸脱氢酶在甲状腺癌中表现出很高的活性。在伴有严重纤维硬化的桥本甲状腺炎中发现活性最低。以直方图形式呈现的细胞光度测量数据显示曲线右偏，核体积和核酸含量呈现多峰、不规则形态，这与所研究甲状腺疾病的细胞学特征一致。核体积与核酸含量之间的线性回归分析表明，甲状腺癌和甲状腺功能正常的甲状腺肿中的相关性降低。
