Tasca C, Stefaneanu L
Acta Histochem. 1977;60(2):261-72. doi: 10.1016/S0065-1281(77)80009-3.
The authors studied the cytological and cytophotometrical aspects in imprints from freshly surgically removed thyroids with the following diseases: nodular goiter, Graves' disease, lymphofibrous chronic thyroiditis, folliculo-papillary cancer, medullary carcinoma and undifferentiated carcinoma. In all the cases the cytological aspects were confirmed by the histopathological diagnosis in paraffin sections. The dextrodeviation and the plurimodal irregular aspects of nucleic acid content and nuclear volumes histograms were in agreement with the cytological features. In addition the linear regression analysis disclosed a diminished correlation between nuclear volumes and the content of nucleic acids paralleling the cellular dedifferentiation.
结节性甲状腺肿、格雷夫斯病、淋巴细胞性慢性甲状腺炎、滤泡乳头状癌、髓样癌和未分化癌。在所有病例中，石蜡切片的组织病理学诊断证实了细胞学特征。核酸含量和核体积直方图的右旋偏差和多峰不规则特征与细胞学特征一致。此外，线性回归分析显示，核体积与核酸含量之间的相关性降低，这与细胞去分化情况平行。
