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[蜂蜜、蜂王浆和蜂胶对加速大鼠实验性胃溃疡醋酸愈合的影响]

[Influence of honey, royal jelly and propolis on accelerating acetate healing of experimental gastric ulcers in rats].

作者信息

Belostotskiĭ N I, Kas'ianenko V I, Dubtsova E A, Lazebnik L B

出版信息

Eksp Klin Gastroenterol. 2009(6):46-50.

Abstract

This study examines gastric acetic ulcer healing in the rat after administration of honey, royal jelly and propolis into the stomach. Chronic gastric ulcers were induced in male Wistar rats by the application of 100% acetic acid to the serosal surface of the stomach on 60 sec. Bee-keeping products were administrated into the stomach from 2nd to 7th day after acetic ulcer induction. On 7th day animals were killed, and ulcer area was measured in mm2. In gastric juice pH and activity of pepsin were measured. The healing of acetic ulcers is accelerated with the administration of honey, royal jelly or propolis during six days. The largest healing effect was demonstrated with propolis and royal jelly, smaller one with the honey. It was revealed decrease of stomach acid secretion in the rats, which have received bee-keeping products versus the rats of control group.

摘要

本研究考察了给大鼠胃内给予蜂蜜、蜂王浆和蜂胶后胃醋酸溃疡的愈合情况。通过在雄性Wistar大鼠胃浆膜表面涂抹100%醋酸60秒诱导慢性胃溃疡。在醋酸溃疡诱导后的第2天至第7天给大鼠胃内给予蜂产品。第7天处死动物,测量溃疡面积(单位为mm²)。同时测量胃液pH值和胃蛋白酶活性。给予蜂蜜、蜂王浆或蜂胶6天可加速醋酸溃疡的愈合。蜂胶和蜂王浆的愈合效果最显著,蜂蜜的效果稍小。结果显示,与对照组大鼠相比,接受蜂产品的大鼠胃酸分泌减少。

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