基于5'-非翻译区的印度古典猪瘟病毒分离株系统发育分析。
5'-UTR-based phylogenetic analysis of Classical swine fever virus isolates from India.
作者信息
Desai G S, Sharma A, Kataria R S, Barman N N, Tiwari A K
机构信息
High Security Animal Disease Laboratory, Indian Veterinary Research Institute, Bhopal, India.
出版信息
Acta Virol. 2010;54(1):79-82. doi: 10.4149/av_2010_01_79.
Classical swine fever (CSF) caused by Classical swine fever virus (CSFV) is a globally significant disease of pigs. Genetic typing of CSFV isolates can help in understanding the epidemiology of disease and trace down the source of outbreak. 5'-UTR sequence analysis and subsequent genetic classification of nine CSFV field isolates from India indicated that 3 isolates belonged to genotype 2.1 and were closely related to European CSFV strains. The remaining 6 isolates belonged to genotype 1 that contained old and new strains. However, the genotype 2.1 group consisted of recent field isolates only. The study showed circulation of both genotypes 1 and 2.1 in north-eastern part of India.
由经典猪瘟病毒（CSFV）引起的经典猪瘟（CSF）是一种在全球范围内对猪具有重要影响的疾病。CSFV分离株的基因分型有助于了解疾病的流行病学情况并追查疫情源头。对来自印度的9株CSFV野外分离株进行5'-UTR序列分析及后续基因分类表明，3株属于2.1基因型，且与欧洲CSFV毒株密切相关。其余6株属于1基因型，其中包含旧毒株和新毒株。然而，2.1基因型组仅由近期的野外分离株组成。该研究表明1基因型和2.1基因型在印度东北部均有传播。
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