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美国西部地区县级艾滋病诊所中感染艾滋病毒的妇女进行宫颈癌和乳腺癌筛查的频率。

Frequency of cervical cancer and breast cancer screening in HIV-infected women in a county-based HIV clinic in the Western United States.

机构信息

Department of Obstetrics and Gynecology, Stanford University, Palo Alto, California, USA.

出版信息

J Womens Health (Larchmt). 2010 Apr;19(4):709-12. doi: 10.1089/jwh.2009.1412.

Abstract

BACKGROUND

Women's primary-care services are frequently dispensed to HIV-infected women through HIV specialty clinics. Our objective was to evaluate cervical cancer and breast cancer screening practices in a county-based HIV clinic in San Mateo, California.

METHODS

This was a retrospective cohort study of medical records of HIV-infected women obtaining HIV care at this site.

RESULTS

Between January 1, 2002 and December 31, 2006, 69 women were documented to have at least 12 months of medical care at the clinic. Median followup time was 51 months. Over 253 person-years of followup, there were 656 pap smears performed per 1,000 person-years; 77.9% of women had at least one Pap smear during the study time period. A total of 59.5% (47/79) of normal pap smears had a followup pap smear within 18 months; 62.0% of abnormal pap smears had a followup pap smear within 12 months. A CD4 count of less than 200 cells/mm(3) was associated with not receiving a pap smear in multivariable analysis. Mammogram screening was performed on 64.7% of women aged 40 or older.

CONCLUSIONS

Based on the results of this study, the majority of HIV-infected women at this clinic received cervical and breast cancer screening at some point during their care. Only two-thirds of abnormal pap smear results had followup pap smear screening within a year. With the increased risk of cervical cancer in HIV-infected women, efforts should be made to promote cervical cancer screening, particularly in high-risk women.

摘要

背景

妇女的初级保健服务经常通过艾滋病毒专科诊所向艾滋病毒感染者妇女提供。我们的目的是评估加利福尼亚州圣马特奥县一个以艾滋病为基础的诊所的宫颈癌和乳腺癌筛查做法。

方法

这是对在该地点获得艾滋病毒护理的艾滋病毒感染者妇女的医疗记录进行的回顾性队列研究。

结果

2002 年 1 月 1 日至 2006 年 12 月 31 日期间,有 69 名妇女被记录在案,在诊所接受了至少 12 个月的医疗护理。中位随访时间为 51 个月。在超过 253 人年的随访期间,每 1000 人年进行 656 次巴氏涂片检查;77.9%的妇女在研究期间至少进行了一次巴氏涂片检查。共有 59.5%(47/79)的正常巴氏涂片在 18 个月内进行了后续巴氏涂片检查;62.0%的异常巴氏涂片在 12 个月内进行了后续巴氏涂片检查。在多变量分析中,CD4 计数小于 200 个细胞/mm(3)与未进行巴氏涂片检查有关。64.7%的 40 岁或以上妇女接受了乳房 X 光筛查。

结论

根据这项研究的结果,该诊所的大多数艾滋病毒感染者妇女在其护理过程中的某个时候接受了宫颈癌和乳腺癌筛查。只有三分之二的异常巴氏涂片检查结果在一年内进行了后续巴氏涂片检查筛查。鉴于艾滋病毒感染者宫颈癌风险增加,应努力促进宫颈癌筛查,特别是在高危妇女中。

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