Ulrich Reiner, Böer Michael, Herder Vanessa, Spitzbarth Ingo, Hewicker-Trautwein Marion, Baumgärtner Wolfgang, Wohlsein Peter
Department of Pathology, University of Veterinary Medicine Hannover, Bünteweg, Hannover, Germany.
J Med Primatol. 2010 Jun;39(3):160-5. doi: 10.1111/j.1600-0684.2010.00405.x. Epub 2010 Feb 19.
Entamoeba (E.) histolytica is an obligate parasite of humans and non-human primates.
This report describes the pathomorphological, immunohistological, and microbiological findings of fatal E. histolytica infection in two mantled guerezas (Colobus guereza) and one Hanuman langur (Semnopithecus entellus) from an epizootic outbreak of amebiasis in an open-range recreation park.
Pathomorphological examination revealed multifocal necrotizing and granulomatous hepatitis with intralesional protozoan trophozoites in all three cases. In addition, necrotizing and ulcerative gastritis was detected in both mantled guerezas. Furthermore, oligofocal acute pulmonary embolization was detected in one of these cases. No extra-hepatic lesions were observed in the Hanuman langur. Immunohistological examination confirmed the etiologic diagnosis of E. histolytica-induced lesions.
Although E. histolytica is a rarely diagnosed pathogen in Western European countries, veterinarians and animal keepers involved in handling and care taking of non-human primates should be aware of the potential threat caused by this zoonotic parasite.
溶组织内阿米巴是人类和非人类灵长类动物的专性寄生虫。
本报告描述了在一个开放式休闲公园发生的阿米巴病 epizootic 疫情中，两只黑白疣猴（疣猴属）和一只哈努曼叶猴（长尾叶猴属）因致命性溶组织内阿米巴感染的病理形态学、免疫组织学和微生物学发现。
病理形态学检查显示，所有三例均有多灶性坏死性和肉芽肿性肝炎，病灶内有原生动物滋养体。此外，在两只黑白疣猴中均检测到坏死性和溃疡性胃炎。此外，在其中一例中检测到寡灶性急性肺栓塞。在哈努曼叶猴中未观察到肝外病变。免疫组织学检查证实了溶组织内阿米巴所致病变的病因诊断。
尽管溶组织内阿米巴在西欧国家是一种很少被诊断出的病原体，但参与处理和照顾非人类灵长类动物的兽医和动物饲养员应意识到这种人畜共患寄生虫所造成的潜在威胁。
