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2008 年军团病爆发期间办公人员庞蒂亚克热样疾病的调查。

Investigation of Pontiac-like illness in office workers during an outbreak of Legionnaires' disease, 2008.

机构信息

Health Protection Surveillance Centre, Dublin, Ireland.

出版信息

Epidemiol Infect. 2010 Nov;138(11):1667-73. doi: 10.1017/S0950268810000403. Epub 2010 Mar 5.

DOI:10.1017/S0950268810000403
PMID:20202281
Abstract

In July 2008, office workers in Dublin complained of influenza-like illness preceding and interspersing two cases of notified Legionnaires' disease. Legionella pneumophila serogroup 1 was identified in both cooling towers supplying the office. A retrospective cohort study was undertaken to investigate possible Pontiac fever (PF). Forty-seven employees (23%) met the clinical case definition for PF but confirmatory testing was negative. Exposure to the smoking area situated beside the cooling towers was associated with an increased risk of PF (RR 2.4, 95% CI 1.5-3.8). The diagnosis of PF should be considered when many persons exposed to a possible reservoir of Legionella spp. present with flu-like symptoms. More sensitive microbiological tests would allow better confirmation and more comprehensive reporting of PF. Early detection is vital to prevent potentially severe illness and outbreaks of PF or Legionnaires' disease.

摘要

2008 年 7 月,都柏林的上班族抱怨流感样疾病,在此之前和之后各有两例已通报的军团病。在为该办公室供水的两座冷却塔中均发现了嗜肺军团菌血清群 1。开展了一项回顾性队列研究,以调查可能的庞蒂亚克热(PF)。47 名员工(23%)符合 PF 的临床病例定义,但确认检测呈阴性。暴露于位于冷却塔旁的吸烟区与 PF 风险增加相关(RR 2.4,95%CI 1.5-3.8)。当许多接触军团菌属可能储存库的人出现流感样症状时,应考虑 PF 的诊断。更敏感的微生物检测将允许更好地确认和更全面地报告 PF。早期发现对于预防潜在的严重疾病以及 PF 或军团病的爆发至关重要。

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