Department of Public Health, Health Services Executive, Dublin, Ireland.
J Environ Public Health. 2010;2010:463926. doi: 10.1155/2010/463926. Epub 2010 Apr 15.
In June and July 2008, two office workers were admitted to a Dublin hospital with Legionnaires' disease. Investigations showed that cooling towers in the basement car park were the most likely source of infection. However, positive results from cooling tower samples by polymerase chain reaction (PCR) did not correlate with subsequent culture results. Also, many employees reported Pontiac fever-like morbidity following notification of the second case of Legionnaires' disease. In total, 54 employees attended their general practitioner or emergency department with symptoms of Legionnaires' disease or Pontiac fever. However, all laboratory tests for Legionnaires' disease or Pontiac fever were negative. In this investigation, email was used extensively for active case finding and provision of time information to employees and medical colleagues. We recommend clarification of the role of PCR in the diagnosis of legionellosis and also advocate for a specific laboratory test for the diagnosis of the milder form of legionellosis as in Pontiac fever.
2008 年 6 月和 7 月,两名上班族因军团病住进都柏林一家医院。调查显示,地下室停车场的冷却塔是最有可能的感染源。然而,聚合酶链反应(PCR)检测冷却塔样本的阳性结果与随后的培养结果没有相关性。此外,第二例军团病病例通报后,许多员工报告出现庞蒂亚克热样发病率。共有 54 名员工因军团病或庞蒂亚克热的症状就诊于他们的全科医生或急诊部。然而,所有军团病或庞蒂亚克热的实验室检测均为阴性。在这项调查中,电子邮件被广泛用于主动发现病例,并向员工和医疗同事提供时间信息。我们建议明确 PCR 在军团病诊断中的作用,并倡导针对轻度军团病(如庞蒂亚克热)的特定实验室检测。