Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Emerg Infect Dis. 2010 Mar;16(3):412-7. doi: 10.3201/eid1603.091028.
In August 2008, Texas authorities and the Centers for Disease Control and Prevention investigated reports of increased numbers of febrile rash illnesses in Austin to confirm the causative agent as Rickettsia typhi, to assess the outbreak magnitude and illness severity, and to identify potential animal reservoirs and peridomestic factors that may have contributed to disease emergence. Thirty-three human cases of confirmed murine typhus were identified. Illness onset was reported from March to October. No patients died, but 23 (70%) were hospitalized. The case-patients clustered geographically in central Austin; 12 (36%) resided in a single ZIP code area. Specimens from wildlife and domestic animals near case-patient homes were assessed; 18% of cats, 44% of dogs, and 71% of opossums had antibodies reactive to R. typhi. No evidence of R. typhi was detected in the whole blood, tissue, or arthropod specimens tested. These findings suggest that an R. typhi cycle involving opossums and domestic animals may be present in Austin.
2008 年 8 月，德克萨斯州当局和疾病控制与预防中心调查了奥斯汀报告的发热皮疹病例增多的情况，以确认病因是伤寒立克次体，评估疫情规模和疾病严重程度，并确定可能导致疾病出现的潜在动物宿主和家庭周围因素。确定了 33 例确诊的鼠型斑疹伤寒病例。发病报告从 3 月到 10 月。没有病人死亡，但 23 人（70%）住院。病例患者在奥斯汀市中心呈地理聚集性；12 例（36%）居住在一个单一的邮政编码区域。评估了病例患者家附近野生动物和家养动物的标本；18%的猫、44%的狗和 71%的负鼠对伤寒立克次体有抗体反应。在测试的全血、组织或节肢动物标本中均未检测到伤寒立克次体。这些发现表明，涉及负鼠和家养动物的伤寒立克次体循环可能存在于奥斯汀。
