2006 年法国留尼汪岛孕妇感染基孔肯雅热病毒。
Chikungunya virus infection during pregnancy, Reunion, France, 2006.
机构信息
Centre Hospitalier Régional de la Réunion, Saint-Denis, France.
出版信息
Emerg Infect Dis. 2010 Mar;16(3):418-25. doi: 10.3201/eid1603.091403.
Abstract
Mother-to-child transmission of chikungunya virus was reported during the 2005-2006 outbreak on Reunion Island, France. To determine the effects of this virus on pregnancy outcomes, we conducted a study of pregnant women in Reunion in 2006. The study population was composed of 1,400 pregnant women (628 uninfected, 658 infected during pregnancy, 27 infected before pregnancy, and 87 infected on unknown dates). We compared pregnancy outcomes for 655 (628 + 27) women not infected during pregnancy with 658 who were infected during pregnancy. Infection occurred during the first trimester for 15% of the infected women, the second for 59%, and the third for 26%. Only hospital admission during pregnancy differed between infected and uninfected women (40% vs. 29%). Other outcomes (cesarean deliveries, obstetric hemorrhaging, preterm births, stillbirths after 22 weeks, birthweight, congenital malformations, and newborn admissions) were similar. This virus had no observable effect on pregnancy outcomes.
摘要
2005-2006 年法国留尼汪岛爆发基孔肯雅热期间有母婴垂直传播的报告。为了确定该病毒对妊娠结局的影响，我们对 2006 年留尼汪的孕妇进行了一项研究。研究人群由 1400 名孕妇（628 名未感染、658 名妊娠期间感染、27 名妊娠前感染、87 名感染日期未知）组成。我们比较了 655 名（628+27）未在妊娠期间感染的孕妇与 658 名妊娠期间感染的孕妇的妊娠结局。感染发生在妊娠早期的孕妇占 15%，妊娠中期的占 59%，妊娠晚期的占 26%。仅妊娠期间住院治疗在感染和未感染孕妇之间存在差异（40% vs. 29%）。其他结局（剖宫产、产科出血、早产、22 周后死胎、出生体重、先天性畸形和新生儿入院）相似。该病毒对妊娠结局没有明显影响。
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