基孔肯雅热。
Chikungunya fever.
机构信息
Virology Unit, Department of Biomedical Sciences, Institute of Tropical Medicine Antwerp, Antwerp, Belgium.
Unité de Recherche en Pharmaco-Immunologie (UR-EPI), Université et CHU de La Réunion, Saint-Denis, France.
出版信息
Nat Rev Dis Primers. 2023 Apr 6;9(1):17. doi: 10.1038/s41572-023-00429-2.
Abstract
Chikungunya virus is widespread throughout the tropics, where it causes recurrent outbreaks of chikungunya fever. In recent years, outbreaks have afflicted populations in East and Central Africa, South America and Southeast Asia. The virus is transmitted by Aedes aegypti and Aedes albopictus mosquitoes. Chikungunya fever is characterized by severe arthralgia and myalgia that can persist for years and have considerable detrimental effects on health, quality of life and economic productivity. The effects of climate change as well as increased globalization of commerce and travel have led to growth of the habitat of Aedes mosquitoes. As a result, increasing numbers of people will be at risk of chikungunya fever in the coming years. In the absence of specific antiviral treatments and with vaccines still in development, surveillance and vector control are essential to suppress re-emergence and epidemics.
摘要
基孔肯雅热病毒广泛分布于热带地区，可引起基孔肯雅热的反复暴发。近年来，该病毒已侵袭东非和中非、南美洲和东南亚的人群。病毒通过埃及伊蚊和白纹伊蚊传播。基孔肯雅热的特征是严重的关节痛和肌痛，可持续数年，对健康、生活质量和经济生产力有很大的不利影响。气候变化的影响以及商业和旅行的日益全球化导致了埃及伊蚊栖息地的扩大。因此，在未来几年中，将有越来越多的人面临基孔肯雅热的风险。由于缺乏特定的抗病毒治疗方法，疫苗仍在开发中，监测和病媒控制对于抑制再次出现和流行至关重要。
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