Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Ophthalmology. 2010 May;117(5):972-5. doi: 10.1016/j.ophtha.2009.10.020. Epub 2010 Mar 3.
To report a case of macular injury caused by prolonged exposure to a flash from the plasma formed at the focus of a femtosecond laser.
Interventional case report.
A patient with macular injury caused by sustained observation of the plasma flash produced by a femtosecond laser.
The patient was examined with complete ophthalmologic evaluation (including Amsler grid test, funduscopy, fluorescein angiography, and optical coherence tomography [OCT]) at 3 hours, 1 month, and 6 months after injury. The injured right eye received a retrobulbar injection of 40 mg triamcinolone acetonide (TransTon), at 4 hours and at 10 days after injury, respectively.
Visual acuity, ophthalmoscopic, and OCT findings.
Three hours after injury, the best-corrected visual acuity of the right eye was 20/30 with a very small relative scotoma nasal to fixation. Funduscopy disclosed a well-circumscribed, yellow-white spot lesion located immediately temporal to the foveal center. As time passed, the patient's vision returned to 20/20 and the scotoma and retinal abnormalities had become less prominent, but were still present. In the acute stage, OCT showed a hyperreflective lesion involved all foveal retinal layers. At 1 and 6 months of follow-up, OCT revealed abnormal reflectivity located within the outer foveal retina.
Prolonged viewing of a plasma flash induced by a focused femtosecond laser in the air without eye protection may produce persistent damage to the retina. The observed macular injury was probably the result of a combination of thermal and photochemical damage.
报告一例因长时间观察飞秒激光焦点处形成的等离子体闪光而导致的黄斑损伤。
介入性病例报告。
一名因长时间观察飞秒激光产生的等离子体闪光而导致黄斑损伤的患者。
患者在损伤后 3 小时、1 个月和 6 个月接受了全面眼科评估(包括 Amsler 网格测试、眼底检查、荧光素血管造影和光学相干断层扫描[OCT])。受伤右眼分别在损伤后 4 小时和 10 天接受了 40mg 曲安奈德(TransTon)球后注射。
视力、眼底和 OCT 结果。
损伤后 3 小时,右眼最佳矫正视力为 20/30,伴有固定鼻侧的小相对暗点。眼底检查显示位于黄斑中心颞侧的边界清晰的黄白色点状病变。随着时间的推移,患者的视力恢复到 20/20,暗点和视网膜异常变得不那么明显,但仍存在。在急性期,OCT 显示一个高反射性病变累及所有黄斑视网膜层。在 1 个月和 6 个月的随访中,OCT 显示外黄斑视网膜内存在异常反射。
长时间观察无眼部保护的空气中聚焦飞秒激光产生的等离子体闪光可能会对视网膜造成持续损伤。观察到的黄斑损伤可能是热和光化学损伤共同作用的结果。