Research Laboratory LR99ES11, Biochemistry Laboratory, Rabta Hospital, Tunis, Tunisia.
Diabetes Metab. 2010 Jun;36(3):204-8. doi: 10.1016/j.diabet.2009.11.009. Epub 2010 Mar 4.
This study aimed to determine the prevalence of the metabolic syndrome (MetS) and its association with socio-economic status in the population of Great Tunis.
The study included 2712 subjects (1228 men and 1484 women), aged 35-70 years and living in the Great Tunis region, all of whom were recruited between March 2004 and June 2005. The sample was weighted by using the inverse of the response rate according to governorate, district and gender. The MetS was defined according to the National Cholesterol Education Program-Adult Treatment Panel III.
In the studied population, the overall prevalence of the MetS was 31.2%, and it was significantly more frequently seen in women than in men (37.3% vs 23.9%, respectively; P<0.001), as were abdominal obesity (69% vs 21.6%, respectively; P<0.001), high blood pressure (50.3% vs 43.1%, respectively; P<0.001) and low HDL cholesterol (40.6% vs 33.6%, respectively; P<0.001), the most common characteristics of the MetS. Also, the prevalence of the MetS increased with age in both genders, but more so in women. In those aged greater than 55 years, the prevalence of MetS was 56.7% in women and 30.7% in men. An inverse relationship was observed between level of education and prevalence of the MetS in women, with the highest prevalence being in illiterate women and the lowest in those who were university graduates.
The prevalence of the MetS is markedly high within the population of Great Tunis and especially in women. As these findings predict future increases in cardiovascular disease in these populations, substantial efforts need to be made to fight against obesity and sedentary lifestyles to ameliorate the expected poor health outcomes.
本研究旨在确定大突尼斯人群中代谢综合征（MetS）的流行情况及其与社会经济地位的关系。
本研究纳入了 2712 名年龄在 35-70 岁之间、居住在大突尼斯地区的受试者（1228 名男性和 1484 名女性），他们均于 2004 年 3 月至 2005 年 6 月期间被招募。根据省份、地区和性别，采用响应率的倒数对样本进行加权。MetS 根据国家胆固醇教育计划-成人治疗小组 III 进行定义。
在所研究的人群中，MetS 的总体患病率为 31.2%，女性明显高于男性（分别为 37.3%和 23.9%；P<0.001），腹部肥胖（分别为 69%和 21.6%；P<0.001）、高血压（分别为 50.3%和 43.1%；P<0.001）和低 HDL 胆固醇（分别为 40.6%和 33.6%；P<0.001）的患病率也较高，这些都是 MetS 的最常见特征。此外，两性的 MetS 患病率均随年龄增长而增加，但女性更为明显。在 55 岁以上的人群中，女性 MetS 的患病率为 56.7%，男性为 30.7%。女性的受教育程度与 MetS 的患病率呈负相关，文盲女性的患病率最高，大学毕业生的患病率最低。
大突尼斯人群中 MetS 的患病率明显较高，尤其是在女性中。鉴于这些发现预示着这些人群中心血管疾病未来的发病率将会增加，因此需要做出巨大努力来对抗肥胖和久坐不动的生活方式，以改善预期的不良健康结局。
