Minami Tatsuya, Sato Shinpei, Watanabe Yoshitaka, Matsuda Rie, Yotsuya Satoru, Yamada Akishige, Tanaka Teruyuki, Kondo Shintaro, Ebihara Tetsuo, Togo Gouichi, Yamazaki Kazuto, Ishida Yasuo
Department of Gastroenterology, Teikyo Chiba Medical Center, Japan.
Nihon Shokakibyo Gakkai Zasshi. 2010 Mar;107(3):442-8.
We report a case of gastrointestinal stromal tumor (GIST) with liver metastases which was undetectable by B-mode ultrasonography, effectively treated by radiofrequency ablation using contrast-enhanced ultrasonography US. A 43-year-old woman was admitted for the treatment of 6 lesions up to 4cm in diameter, which had emerged from necrotic sites within the liver after imatinib treatment. The recurrent lesions were not detected on B-mode US, and it was difficult to perform radiofrequency ablation (RFA) treatment. Using a contrast-enhanced agent (sonazoid), the recurrent lesions were detected and treated by RFA. RFA is considered to be an effective treatment for GIST with liver metastases that tolerate imatinib administration.
我们报告一例胃肠道间质瘤(GIST)伴肝转移,该病例通过B超无法检测到,而使用超声造影的射频消融术对其进行了有效治疗。一名43岁女性因治疗6个直径达4厘米的病灶入院,这些病灶是在伊马替尼治疗后肝脏坏死部位出现的。B超未检测到复发病灶,难以进行射频消融(RFA)治疗。使用超声造影剂(声诺维)后,检测到复发病灶并进行了RFA治疗。对于耐受伊马替尼治疗的GIST肝转移患者,RFA被认为是一种有效的治疗方法。