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新西兰婴儿猝死研究第一年的结果。

Results from the first year of the New Zealand cot death study.

作者信息

Mitchell E A, Scragg R, Stewart A W, Becroft D M, Taylor B J, Ford R P, Hassall I B, Barry D M, Allen E M, Roberts A P

机构信息

University of Auckland School of Medicine.

出版信息

N Z Med J. 1991 Feb 27;104(906):71-6.

PMID:2020450
Abstract

New Zealand's high mortality rate from the sudden infant death syndrome (SIDS) prompted the development of the New Zealand cot death study. This report of the preliminary analysis of the first year of the data gives the major identified risk factors. One hundred and sixty-two infants who died from SIDS were compared with 589 control infants, who were a representative sample of all hospital births in the study region. Obstetric records were examined and parental interviews were completed in 96% and 89% of subjects respectively. Data were available for all the variables in this study in 95% of those interviewed, thus 128 cases and 503 controls make up the subjects of this report. As expected we confirmed many risk factors for SIDS including: lower socioeconomic status, unmarried mother, young mother, younger school leaving age of mother, younger age of mother at first pregnancy, late attendance at antenatal clinic, nonattendant at antenatal classes, Maori, greater number of previous pregnancies, lower birth weight, shorter gestation, male infant, admission to neonatal intensive care unit. In addition, however, we identified three risk factors which are potentially amenable to modification. These were the prone sleeping position of baby (odds ratio = 3.53, 95% confidence interval 2.26, 5.54), maternal smoking (1-9 cigarettes/day OR = 1.87, 95% CI = 0.98, 3.54; 10-19/day OR = 2.64, 95% CI = 1.47, 4.74; 20+/day OR = 5.06, 95% CI = 2.86, 8.95) and breast feeding (OR = 2.93, 95% CI = 1.84, 4.67).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

新西兰婴儿猝死综合征(SIDS)的高死亡率促使开展了新西兰婴儿床死亡研究。这份对该数据第一年初步分析的报告给出了已确定的主要风险因素。将162名死于SIDS的婴儿与589名对照婴儿进行了比较,这些对照婴儿是研究区域内所有医院出生婴儿的代表性样本。分别对96%和89%的研究对象检查了产科记录并完成了对父母的访谈。在95%接受访谈的对象中可获取本研究所有变量的数据,因此128例病例和503名对照构成了本报告的研究对象。正如预期的那样,我们证实了许多SIDS的风险因素,包括:社会经济地位较低、未婚母亲、年轻母亲、母亲离校年龄较小、母亲首次怀孕时年龄较小、产前诊所就诊晚、未参加产前课程、毛利人、既往怀孕次数较多、出生体重较低、妊娠期较短、男婴、入住新生儿重症监护病房。然而,此外我们还确定了三个可能可以改变的风险因素。这些因素是婴儿俯卧睡眠姿势(优势比=3.53,95%置信区间2.26,5.54)、母亲吸烟(每天1 - 9支香烟,优势比=1.87,95%置信区间=0.98,3.54;每天10 - 19支,优势比=2.64,95%置信区间=1.47,4.74;每天20支及以上,优势比=5.06,95%置信区间=2.86,8.95)以及母乳喂养(优势比=2.93,95%置信区间=1.84,4.67)。(摘要截短至250字)

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