Jáuregui-Barrutia A, Tijero-Merino B, Gómez-Esteban J C, Zarranz J J
Hospital Universitario de Cruces, Baracaldo, Vizcaya, España.
Rev Neurol. 2010 Feb 8;50 Suppl 2:S15-9.
It is well known that patients with Parkinson's disease (PD) and other neurodegenerative diseases very commonly present sleep disorders, and that they possibly share common pathophysiological mechanisms with motor signs.
In the case of REM sleep behaviour disorder, a number of studies have shown that it may appear more than ten years before the motor signs. Although there is no evidence to prove that patients with restless legs syndrome have an increased risk of suffering from PD, the high prevalence of this symptom in PD and the good response to dopamine agonists suggest the existence of a relation between the two conditions.
The impact that these conditions have on patients' quality of life makes it very important to know how to diagnose and treat them.
众所周知，帕金森病（PD）患者和其他神经退行性疾病患者非常普遍地存在睡眠障碍，并且他们可能与运动症状共享共同的病理生理机制。
就快速眼动睡眠行为障碍而言，多项研究表明，它可能在运动症状出现前十多年就出现。虽然没有证据证明不安腿综合征患者患帕金森病的风险增加，但这种症状在帕金森病中的高患病率以及对多巴胺激动剂的良好反应表明这两种情况之间存在关联。
这些病症对患者生活质量的影响使得了解如何诊断和治疗它们非常重要。
