Najafi Mohammad Reza, Chitsaz Ahmad, Askarian Zahra, Najafi Mohammad Amin
Department of Neurology, Isfahan University of Medical Sciences, Isfahan, Iran ; Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Int J Prev Med. 2013 May;4(Suppl 2):S229-33.
Parkinson's disease (PD) is a progressive neurodegenerative disorder causing motor and non-motor symptoms. The latter are common and include autonomic dysfunction, cognitive impairment, and sleep difficulties. Many of the non-motor aspects of PD such as sleep disturbance are more common and significantly affect the day-to-day activities of patients and their quality of life. The most important aim of this study was to evaluate the sleep quality in patients with PD.
This case-control study was performed on patients with PD referred to the Neurology Clinic of our teaching hospital in 2011. Thirty-four patients with PD and 34 healthy people as control group were enrolled in this study. Sleep quality of patients and control was evaluated by Parkinson's disease sleep scale (PDSS) questionnaire. PDSS is a reliable and valid tool to measure sleep disorders in PD.
The mean total PDSS score in patient group was 55.29 (SD = 26.92) indicating moderate to severe sleep disturbances whereas, the mean total score in control group was 20.34 (SD = 10.65). Difference between the two groups' mean scores was significant (P < 0.05).
Our study demonstrated that patients with PD experienced poorer nocturnal sleep quality than the control group.
帕金森病（PD）是一种进行性神经退行性疾病，可导致运动和非运动症状。后者很常见，包括自主神经功能障碍、认知障碍和睡眠困难。PD的许多非运动方面，如睡眠障碍，更为常见，并显著影响患者的日常活动及其生活质量。本研究的最重要目的是评估PD患者的睡眠质量。
本病例对照研究于2011年对转诊至我院教学医院神经科门诊的PD患者进行。本研究纳入了34例PD患者和34名健康人作为对照组。通过帕金森病睡眠量表（PDSS）问卷评估患者和对照组的睡眠质量。PDSS是一种可靠且有效的工具，用于测量PD中的睡眠障碍。
患者组的PDSS总平均分是55.29（标准差=26.92），表明存在中度至重度睡眠障碍，而对照组的总平均分是20.34（标准差=10.65）。两组平均分之间的差异具有统计学意义（P<0.05）。
我们的研究表明，PD患者的夜间睡眠质量比对照组差。
