Fedorenko Grigoriy M, Uzdensky Anatoliy B
Southern Scientific Center RAS, A.B. Kogan Research Institute for Neurocybernetics, Southern Federal University, 194/1, Stachki ave, Rostov-on-Don, 344090, Russian Federation.
J Integr Neurosci. 2009 Dec;8(4):433-40. doi: 10.1142/s0219635209002290.
In order to explore neuroglial relationships in a simple nervous system, the ultrastructure of crayfish stretch receptor, which consists of only two sensory neurons enveloped by satellite glial cells, was studied. Neuronal Golgi complex was oriented such that its output trans-Golgi network usually faced the bundles of microtubules within the neuronal cytoplasm and very rarely to the outer membrane. Therefore, it participates mainly in the processing of proteins transported along microtubules to distal neuron parts rather than those transported to glial cells. Structural triads of submembrane cisterns-vesicles-mitochondria were involved in formation of glial protrusions into the neuronal cytoplasm. The double-wall vesicles within the neuron body were the captured parts of such glial protrusions. Glial protrusions and double-wall vesicles facilitated the neuroglial transport and large-scale delivery of the glial material into the neuron. The neuroglial transport could also be performed by diffusion across the intercellular space. These data indicate the significant neuroglial exchange with cellular components.
为了探究简单神经系统中的神经胶质关系，对小龙虾牵张感受器的超微结构进行了研究，该感受器仅由两个被卫星胶质细胞包裹的感觉神经元组成。神经元高尔基体复合体的方向是，其输出的反式高尔基体网络通常面向神经元胞质内的微管束，很少面向外膜。因此，它主要参与沿着微管运输到神经元远端部分的蛋白质的加工，而不是运输到胶质细胞的蛋白质的加工。膜下池-囊泡-线粒体的结构三联体参与了胶质突起向神经元胞质的形成。神经元胞体内的双壁囊泡是这种胶质突起的捕获部分。胶质突起和双壁囊泡促进了神经胶质运输以及胶质物质向神经元的大规模传递。神经胶质运输也可以通过跨细胞间隙的扩散来进行。这些数据表明神经胶质与细胞成分之间存在显著的交换。
