Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA.
Drugs. 2010 Mar 5;70(4):433-42. doi: 10.2165/11534540-000000000-00000.
The diagnosis of bipolar disorder (BD) in children is increasing, and often requires a comprehensive treatment plan to address a complex array of symptoms and associated morbidities. Pharmacotherapy, in combination with psychotherapeutic interventions, is essential for the treatment and stabilization of disrupted mood. Current evidence collectively demonstrates, by randomized controlled design, that atypical antipsychotics have efficacy for the treatment of acute manic or mixed symptoms in children and adolescents with BD. Additional longitudinal and biological studies are warranted to characterize the effects of atypical antipsychotics on all phases and stages of bipolar illness development in children and adolescents.
儿童双相情感障碍 (BD) 的诊断正在增加，通常需要一个综合治疗计划来解决一系列复杂的症状和相关的病态。药物治疗结合心理治疗干预对于治疗和稳定情绪紊乱至关重要。目前的证据通过随机对照设计共同表明，非典型抗精神病药对于治疗儿童和青少年双相情感障碍的急性躁狂或混合症状具有疗效。需要进行更多的纵向和生物学研究来描述非典型抗精神病药对儿童和青少年双相情感障碍所有阶段和时期的影响。
