Rao Mohan, Rajda Geet, Uppuluri Sarada, Beck G Ronald, Liu Lynn, Bisognano John D
Department of Internal Medicine, Cardiology Division, University of Rochester Medical Center, Rochester, NY, USA.
Rev Recent Clin Trials. 2010 Jan;5(1):35-42. doi: 10.2174/157488710790820526.
Obstructive sleep apnea-hypoapnea syndrome (OSA) is a disorder that results in repetitive occlusion of the airway and hypoxemia during sleep. Epidemiologic studies have associated this disorder with increased cardiovascular morbidity and mortality. Systemic hypertension is prevalent among patients with OSA and has been recognized as a common identifiable cause of hypertension. Nasal continuous positive airway pressure (nCPAP) ventilation is an effective therapy for OSA and it may additionally reduce blood pressure. The use of nCPAP ventilation to treat hypertension in patients with OSA has been studied extensively. However, whether it is effective in treating hypertension in this population remains unclear. This review evaluates the recent literature that investigates the effects of nCPAP ventilation on hypertension in patients with OSA.
阻塞性睡眠呼吸暂停低通气综合征（OSA）是一种在睡眠期间导致气道反复阻塞和低氧血症的疾病。流行病学研究已将这种疾病与心血管发病率和死亡率的增加联系起来。系统性高血压在OSA患者中很常见，并且已被认为是高血压的常见可识别病因。鼻持续气道正压通气（nCPAP）是治疗OSA的有效方法，它还可能降低血压。使用nCPAP通气治疗OSA患者的高血压已得到广泛研究。然而，它在该人群中治疗高血压是否有效仍不清楚。本综述评估了最近研究nCPAP通气对OSA患者高血压影响的文献。
