Ach Koussay, Slim Ines, Ajmi Sihem Trimech, Chaieb Molka Chadli, Beizig Amel Maaroufi, Chaieb Larbi
Department of Endocrinology and Diabetology, Farhat Hached University Hospital, Ibn Jazzar Street, 4002 Soussa, Tunisia.
Cases J. 2010 Jan 18;3:30. doi: 10.1186/1757-1626-3-30.
Seizures with or without trauma may cause fractures that occur commonly in epileptic seizures. Fracture risk is less reported in non-epileptic seizures. Some metabolic conditions leading to a decrease in bone mineral density may cause fractures secondary to non-epileptic seizure.
We describe two cases of non-traumatic acetabular and vertebrae fractures following seizures without history of epilepsy. They occurred in two male patients, 18 and 48 years old suffering respectively from hypercorticism and poorly controlled diabetes mellitus. Seizures, occurring inside hospital, were secondary to hypertensive encephalopathy crisis with hypokaliemia in the first case and severe hypoglycaemia in the second one. Fracture was promoted by a decrease in mineral bone density caused respectively by hypercorticism and diabetic chronic renal failure.
These observations emphasize that fracture prevention among patients with decreased mineral bone density should include the avoidance of metabolic causes of seizure.
有或无创伤的癫痫发作都可能导致骨折，这在癫痫发作中很常见。非癫痫性发作导致骨折风险的报道较少。一些导致骨矿物质密度降低的代谢状况可能会引发非癫痫性发作继发的骨折。
我们描述了两例无癫痫病史的癫痫发作后非创伤性髋臼和椎骨骨折的病例。这两例发生在两名男性患者身上，年龄分别为18岁和48岁，分别患有皮质醇增多症和控制不佳的糖尿病。在医院内发生的癫痫发作，第一例继发于伴有低钾血症的高血压脑病危象，第二例继发于严重低血糖。骨折分别由皮质醇增多症和糖尿病慢性肾衰竭导致的骨矿物质密度降低所促发。
这些观察结果强调，骨矿物质密度降低的患者预防骨折应包括避免癫痫发作的代谢原因。
