Department of Pathology and Laboratory Medicine, Rhode Island Hospital, Providence, RI, USA.
Diagn Pathol. 2010 Jan 21;5:6. doi: 10.1186/1746-1596-5-6.
The presence of crystalline inclusions in plasma cell myeloma is a rare phenomenon and cases have been reported with rod, needle, and rectangular shaped crystals. Here, we present a case of IgG lambda restricted plasma cell myeloma with rhomboid shaped intracellular crystalline inclusions and extracellular crystal depositions in the bone marrow. Since rhomboid crystal depositions can be seen in other clinical conditions such as pseudogout, this case invites consideration of plasma cell myeloma in the differential diagnosis of patients with rhomboid crystalline deposition in the bone marrow and in sites/organs other than the bone marrow.
浆细胞骨髓瘤中存在结晶包含物是一种罕见现象，已有报道显示存在杆状、针状和矩形晶体。在此，我们报告一例 IgG λ 型限制性浆细胞骨髓瘤，其具有菱形细胞内结晶包含物和骨髓中外泌体晶体沉积。由于菱形晶体沉积也可见于其他临床情况，如假性痛风，因此在骨髓和骨髓以外的其他部位/器官中出现菱形晶体沉积的患者鉴别诊断中，应考虑浆细胞骨髓瘤。
