Gotlieb A I, Freeman M R, Salerno T A, Lichtenstein S V, Armstrong P W
Department of Pathology, St. Michael's Hospital, University of Toronto, Canada.
Mod Pathol. 1991 Jan;4(1):75-80.
Nineteen patients with refractory unstable angina who were undergoing aortocoronary bypass were studied to assess the extent of platelet aggregation present in the microvasculature. Ultrastructural findings on the morphology of cardiac muscle and microvasculature were correlated with the findings on coronary angiograms and thallium scans. There were no significant correlations. The presence of platelet aggregates was identified in four biopsies, two of which had thrombus by angiographic criteria. Biopsy in areas with thallium defects revealed an increased prevalence of white blood cells without acute myocardial infarction. This study confirms the presence of platelet aggregates in patients with unstable angina, albeit at a reduced frequency when compared with autopsy studies.
对19例正在接受主动脉冠状动脉搭桥手术的难治性不稳定型心绞痛患者进行了研究，以评估微血管系统中血小板聚集的程度。心肌和微血管形态的超微结构发现与冠状动脉造影和铊扫描的结果相关。未发现显著相关性。在4份活检标本中发现了血小板聚集体，其中2份根据血管造影标准有血栓形成。在铊扫描缺损区域进行的活检显示，白细胞患病率增加，但无急性心肌梗死。本研究证实不稳定型心绞痛患者存在血小板聚集体，尽管与尸检研究相比，其发生率有所降低。
